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Browsing University of Hertfordshire by Author "Sarasola, P."
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Ampicillin and its congener prodrugs in the horse
Sarasola, P.; McKellar, Quintin (1994-03)Ampicillin is an antibiotic commonly administered to horses by both the intramuscular (i.m.) and the intravenous (i.v.) route. Its physicochemical properties restrict its absorption after oral administration and explain ... -
Disposition of ampicillin sodium in horses, ponies and donkeys after intravenous administration
Horspool, L. J.; Sarasola, P.; McKellar, Quintin (1992-02) -
Effect of changes in urine pH on plasma pharmacokinetic variables of ampicillin sodium in horses
Sarasola, P.; Horspool, L. J.; McKellar, Quintin (1992)The effect of urine pH on plasma disposition of ampicillin sodium was evaluated. A single dose of 10 mg/kg of body weight was administered IV to Thoroughbreds with alkaline (pH greater than 8.0) or acidic (pH less than ... -
Effect of probenecid on disposition kinetics of ampicillin in horses
Sarasola, P.; McKellar, Quintin (1992-08)The effect of an oral dose of probenecid on the disposition kinetics of ampicillin was determined in four horses. An intravenous bolus dose (10 mg/kg) of ampicillin sodium was administered to the horses on two occasions. ... -
Parasitosis internas del caballo, Sustrai Revista
Sarasola, P.; McKellar, Quintin (1991) -
Pharmacokinetic and pharmacodynamic profiles of danofloxacin administered by two dosing regimens in calves infected with Mannheimia (Pasteurella) haemolytica
Sarasola, P.; Lees, P.; AliAbadi, F.S.; McKellar, Quintin; Donachie, W.; Marr, K.A.; Sunderland, S.J.; Rowan, T.G. (2002-09)The pharmacokinetics and pharmacodynamics of danofloxacin in calves with induced Mannheimia (Pasteurella) haemolytica pneumonia were evaluated. Calves received either saline as an intravenous (IV) bolus or danofloxacin ... -
Pharmacokinetics and applications of ampicillin sodium as an intravenous infusion in the horse
Sarasola, P.; McKellar, Quintin (1993-03)A regime for administration of ampicillin sodium by continuous intravenous infusions to horses was designed. The aim was to achieve plasma ampicillin concentrations between 5 and 10 micrograms/ml over a 4-h period. A 2 ... -
Pharmacokinetics of bacampicillin in equids
Sarasola, P.; McKellar, Quintin (1995)Bacampicillin hydrochloride is an ester prodrug that is hydrolyzed to ampicillin after its absorption from the gastrointestinal tract. It was administered intragastrically at a dose rate of 13.5 mg/kg of body weight to ... -
Secondary bacterial infections following an outbreak of equine influenza
Sarasola, P.; Taylor, D. J.; Love, S.; McKellar, Quintin (1992-11)