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Browsing University of Hertfordshire by Author "Shafaie, Sara"
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Diffusion through the ex vivo vitreal body - bovine, porcine, and ovine models are poor surrogates for the human vitreous
Shafaie, Sara; Hutter, Victoria; Brown, Marc; Cook, Michael; Chau, David (2018-10-25)The human vitreous humour is a complex gel structure whose composition and physical properties can vary considerably from person to person and also change with age. To date, the viscoelastic properties of the human vitreous ... -
In Vitro Cell Models for Ophthalmic Drug Development Applications
Shafaie, Sara; Hutter, Victoria; Cook, Michael T.; Brown, Marc; Chau, David Y.S. (2016-04-20)Tissue engineering is a rapidly expanding field that aims to establish feasible techniques to fabricate biologically equivalent replacements for diseased and damaged tissues/organs. Emerging from this prospect is the ... -
Influence of surface geometry on the culture of human cell lines: a comparative study using flat, round-bottom and v-shaped 96 well plates
Shafaie, Sara; Hutter, Victoria; Brown, Marc; Cook, Michael; Chau, David (2017-10-30)In vitro cell based models have been invaluable tools for studying cell behaviour and for investigating drug disposition, toxicity and potential adverse effects of administered drugs. Within this drug discovery pipeline, ...