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The application and limitations of mathematical modelling in the prediction of permeability across mammalian skin and polydimethylsiloxane membranes
(2011-11)
Objectives: Predicting the rate of percutaneous absorption of a drug is an important issue with the increasing use of the skin as a means of moderating and controlling drug delivery. One key feature of this problem domain ...
Transit timing observations from Kepler. I. : Statistical analysis of the first four months
(2011-11-01)
The architectures of multiple planet systems can provide valuable constraints on models of planet formation, including orbital migration, and excitation of orbital eccentricities and inclinations. NASA's Kepler mission has ...
The 6-GHz methanol multibeam maser catalogue - III. Galactic longitudes 330° to 345°
(2011-11-01)
We present results from the third portion of the Methanol Multibeam Galactic plane survey of masers at 6668 MHz. It covers the longitude range 330°-345°, yielding 198 masers, of which more than 40per cent are new discoveries. ...
Key factors influencing decision making in relation to elder financial abuse : A case scenario study of certainty, likelihood of taking action, and action taken.
(2011-11)
Little is know about the factors that influence decision making by health, social care and banking professionals in relation to detecting and preventing elder financial abuse. The research questions for this study were, ...
The effects of dsRNA mycoviruses on growth and murine virulence of Aspergillus fumigatus
(2011-11)
Some isolates of the opportunistic human pathogenic fungus Aspergillus fumigatus are known to be infected with mycoviruses. The dsRNA genomes of two of these mycoviruses, which include a chrysovirus and a partitivirus, ...
Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex
(2011-11-01)
The cell surface interaction between bacterial lipopolysaccharide (LPS), Toll-like receptor 4 (TLR4) and MD-2 is central to bacterial sepsis syndromes and wound healing. We have shown that a generation (G) 3.5 polyamidoamine ...
Complex scattered radiation fields and multiple magnetic fields in the protostellar cluster in NGC 2264
(2011-11-01)
Near-infrared imaging polarimetry in the J, H, and K-s bands has been carried out for the protostellar cluster region around NGC 2264 IRS 2 in the Monoceros OB1 molecular cloud. Various infrared reflection nebula clusters ...
Bringing the imaginary back into play
(2011-11)
The term ‘ludic’ can be linked to many aspects of play and games, but what does it mean to be playful? Using examples of various augmented reality game, this paper will examine the role of mimicry in play as a way of ...
Resistance of Malus domestica fruit to Botrytis cinerea depends on endogenous ethylene biosynthesis
(2011-11-01)
The plant hormone ethylene regulates fruit ripening, other developmental processes, and a subset of defense responses. Here, we show that 1-aminocyclopropane-1-carboxylic acid synthase (ACS)-silenced apple (Malus domestica) ...