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Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells

Njoh, Kerenza L.; Patterson, Laurence H.; Zloh, Mire; Wiltshire, Marie; Fisher, Janet; Chappell, Sally; Ameer-Beg, Simon; Bai, Yanhong; Matthews, Daniel; Errington, Rachel J.; Smith, Paul J. (2006-08)

We report on the potential DNA binding modes and spectral characteristics of the cell-permeant far red fluorescent DNA dye, DRAQ5, in solution and bound within intact cells. Our aim was to determine the constraints for its ...