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Stochastic model of template-directed elongation processes in biology
(2010)
We present a novel modular, stochastic model for biological template-based linear chain elongation processes. In this model, elongation complexes (ECs; DNA polymerase, RNA polymerase, or ribosomes associated with nascent ...
Genetic algorithms and their application to in silico evolution of genetic regulatory networks
(2010)
A genetic algorithm (GA) is a procedure that mimics processes occurring in Darwinian evolution to solve computational problems. A GA introduces variation through "mutation" and "recombination" in a "population" of possible ...