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Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells
(2018-11-01)
First-generation immune checkpoint inhibitors, including anti-CTLA-4 and anti-programmed death 1 (anti-PD-1) antibodies, have led to major clinical progress, yet resistance frequently leads to treatment failure. Thus, new ...
Sebomic identification of sex- and ethnicity-specific variations in residual skin surface components (RSSC) for bio-monitoring or forensic applications
(2018-08-21)
Background: “Residual skin surface components” (RSSC) is the collective term used for the superficial layer of sebum, residue of sweat, small quantities of intercellular lipids and components of natural moisturising factor ...
The impact of dementia on service use by individuals with a comorbid health condition: a comparison of two cross-sectional analyses conducted approximately ten-years apart
(2018-07-24)
Background The presence of concomitant medical conditions in people with dementia is common. Dementia may be related to differential use of health, social and informal care. Methods Data from two large UK population-based ...
Work of the NHS England Youth Forum and its effect on health services.
(2018-07-11)
AIM: To examine the role of members of the NHS England Youth Forum (NHSEYF) and the strategies used to influence health service provision for children and young people. METHOD: An evaluative mixed-methods study was ...
Prevalence of emergency contraceptive pill use among Spanish adolescent girls and their family and psychological profiles
(2018-05-16)
Background:Adolescent girls’ family context and psychological characteristics play important roles in their sexual behavior, including the use of the emergency contraceptive pill (ECP). This study aims to (1) determine the ...
Evaluation of the implementation of a clinical pharmacy service on an acute internal medicine ward in Italy
(2018-04-10)
Background: Successful implementation of clinical pharmacy services is associated with improvement of appropriateness of prescribing. Both high clinical significance of pharmacist interventions and their high acceptance ...
Association between Diet-Quality Scores, Adiposity, Total Cholesterol and Markers of Nutritional Status in European Adults : Findings from the Food4Me Study
(2018-01-06)
Diet-quality scores (DQS), which are developed across the globe, are used to define adherence to specific eating patterns and have been associated with risk of coronary heart disease and type-II diabetes. We explored the ...