Browsing Research publications by Author "Hutter, Victoria"
Now showing items 21-26 of 26
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Polymer Architecture Effects on Poly(N,N‐Diethyl Acrylamide)‐b‐Poly(Ethylene Glycol)‐b‐Poly(N,N‐Diethyl Acrylamide) Thermoreversible Gels and Their Evaluation as a Healthcare Material
Haddow, Peter J.; da Silva, Marcelo A.; Kaldybekov, Daulet B.; Dreiss, Cecile A.; Hoffman, Ewelina; Hutter, Victoria; Khutoryanskiy, Vitaliy V.; Kirton, Stewart B.; Mahmoudi, Najet; McAuley, William J.; Cook, Michael T. (2021-12-11)Thermoreversible gels which transition between liquid‐like and solid‐like states when warmed have enabled significant novel healthcare technologies. Poly(N,N‐diethyl acrylamide) (PDEA) is a thermoresponsive polymer which ... -
Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies
Pecoraro, Beatrice; Tutone, Marco; Hoffman, Ewelina; Hutter, Victoria; Almerico, Anna Maria; Traynor, Matthew (2019-05-28)The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters. ... -
Profiling alveolar macrophage responses to inhaled compounds using in vitro high content image analysis
Hoffman, Ewelina; Urbano, Laura; Martin, Abigail; Mahendran, Rhamiya; Patel, Aateka; Murnane, Darragh; Page, Clive; Dailey, Lea Ann; Forbes, Ben; Hutter, Victoria (2023-09-01)One of the main hurdles in the development of new inhaled medicines is the frequent observation of foamy macrophage (FM) responses in non-clinical studies in experimental animals, which raises safety concerns and hinders ... -
A quantitative structure-permeability relationship model for split-thickness skin absorption, reasoning for the choice of the database.
Pecoraro, Beatrice; Hoffman, Ewelina; Hutter, Victoria; Traynor, Matthew (2018-06-20)The skin is the largest organ in the human body, protecting the body from xenobiotic invasion (1). Local and systemic drugs may also be administered through the skin, therefore the need to measure the permeability of the ... -
Skin permeation and penetration of mometasone furoate in the presence of emollients: An ex vivo evaluation of clinical application protocols
Beebeejaun, Mubinah T.; Brown, Marc B.; Hutter, Victoria; Kravitz, Laura; McAuley, William J. (2023-06)Background: Topical corticosteroids (TCS) and emollients are developed independently by the pharmaceutical industry but are often used together in practice. There is potential for the TCS and emollient formulations to ... -
Tissue transglutaminase (TG-2) modified amniotic membrane : a novel scaffold for biomedical applications
Chau, David Y.S.; Brown, Sheridan V.; Mather, Melissa L.; Hutter, Victoria; Tint, Naing L.; Dua, Harminder S.; Rose, Felicity R. A. J.; Ghaemmaghami, Amir M. (2012-08)The amniotic membrane (AM) is considered as a natural cell culture substrate and has occasionally been exploited in regenerative medicine especially for ocular surface reconstruction and dermal wound healing applications. ...