Browsing Research publications by Author "Brazier, Jon"
Now showing items 1-20 of 25
-
All models are wrong, but the critical power model is useful.
Muniz, Daniel; Maunder, Ed; Brazier, Jon; Hunter, Ben (2023-11-17) -
Anthropometric and Physiological Characteristics of Elite Male Rugby Athletes
Brazier, Jon; Antrobus, M; Stebbings, G; Day, S; Callus, P; Erskine, R; Bennett, M; Kilduff, L; Williams, A (2020-06-01)This is the first article to review the anthropometric and physiological characteristics required for elite rugby performance within both Rugby Union (RU) and Rugby League (RL). Anthropometric characteristics such as height ... -
Apolipoprotein E Ε4 allele is not associated with elite rugby status but is present in 30% of athletes
Heffernan, S; Kilduff, L; Erskine, R; Day, S; Stebbings, G; Cook, C; A, Grainger; Brazier, Jon; Antrobus, M; Williams, A (2018-07-04)The APOE ε4 allele is a candidate genetic marker for risk and severity of mild traumatic brain injury (mTBI) including sport-related concussion. ε4 allele carriers experience reduced motor rehabilitation outcomes, poorer ... -
An Assessment of the Hopping Strategy and Inter-Limb Asymmetry during the Triple Hop Test: A Test–Retest Pilot Study
Davey, Kyle; Read, Paul; Coyne, Joseph; Jarvis, Paul; Turner, Anthony; Brazier, Jon; Šarabon, Nejc; Jordan, Matthew J.; Bishop, Chris (2021-10-07)The aims of the present study are to: (1) determine within- and between-session reliability of multiple metrics obtained during the triple hop test; and (2) determine any systematic bias in both the test and inter-limb ... -
The Association between Inter-limb Asymmetry and Athletic Performance Tasks: A Season Long Study in Elite Academy Soccer Players
Bishop, C; Read, P; Bromley, T; Brazier, Jon; Jarvis, P; Chavda, Shyam; Turner, Anthony (2020-02-27)The aims of the present study were to determine the association between asymmetry and measures of speed and change of direction speed (CODS) performance throughout a competitive soccer season and, determine if any observed ... -
Association between MAPT polymorphism but not APOE promoter and elite rugby athlete status
Antrobus, M; Brazier, Jon; Herbert, A; Stebbings, G; Day, S; Heffernan, S; Erskine, R; Kilduff, L; Williams, A (2018-07-04)INTRODUCTION: Incidence and outcomes of concussions have been hypothesised to be genetically influenced. The APOE Promoter G219T (rs405509) polymorphism has been associated with differential promoter activity and unfavourable ... -
Association of MMP3 but not TIMP2 gene variants with elite rugby player status and rugby code
Brazier, Jon; Antrobus, M; Herbert, A; Stebbings, G; Day, S; Heffernan, S; Erskine, R; Kilduff, L; Williams, A (2018-07-04)Introduction: Achilles tendon pathology and anterior cruciate ligament rupture are multifactorial conditions for which genetic risk factors have been identified. Single nucleotide polymorphisms (SNPs) within the MMP3 ... -
Bone Mineral Density and Associated Genetic Variants in High-level Caucasian Marathon Runners
Herbert, A; Williams, A; Lockey, S; Erskine, R; Sale, C; Hennis, P; Antrobus, M; Brazier, Jon; Heffernan, S; Day, S; Stebbings, G (2018-07-04)INTRODUCTION:Endurance runners (except those who may have low energy availability) tend to have higher total and/or loading site-specific bone mineral density (BMD) in comparison with non-athletes, most likely due to the ... -
Collagen gene polymorphisms previously associated with resistance to soft-tissue injury are more common in competitive runners than non-athletes
Dines, H; Nixon, J; Lockey, S; Herbert, A; Kipps, C; Pedlar, C; Day, S; Heffernan, S; Antrobus, M; Brazier, Jon; Erskine, R; Stebbings, G; Hall, E; Williams, A (2023-04-01)Single nucleotide polymorphisms (SNPs) of collagen genes have been associated with soft-tissue injury and running performance. However, their combined contribution to running performance is unknown. We investigated the ... -
Concussion-associated gene variant COMT rs4680 is associated with elite rugby athlete status
Antrobus, M; Brazier, Jon; Callus, P; Herbert, A; Stebbings, G; Day, S; Kilduff, L; Bennett, M; Erskine, R; Raleigh, Stuart; Collins, M.; Pitsiladis, Y; Heffernan, S; Williams, A (2023-09-01)Objective: Concussions are common match injuries in elite rugby and reports exist of reduced cognitive function and long-term health consequences that can interrupt or end a playing career and produce continued ill health. ... -
Concussion-Associated Polygenic Profiles of Elite Male Rugby Athletes
Antrobus, Mark R.; Brazier, Jon; Callus, Peter C.; Herbert, Adam J.; Stebbings, Georgina K.; Khanal, Praval; Day, Stephen H.; Kilduff, Liam P.; Bennett, Mark A.; Erskine, Robert M.; Raleigh, Stuart M.; Collins, Malcolm; Pitsiladis, Yannis P.; Heffernan, Shane M.; Williams, Alun G. (2022-05-04)Due to the high-velocity collision-based nature of elite rugby league and union, the risk of sustaining a concussion is high. Occurrence of and outcomes following a concussion are probably affected by the interaction of ... -
Effects of Inter-limb Asymmetries on Acceleration and Change of Direction Speed: A Between-Sport Comparison of Professional Soccer and Cricket Athletes
Bishop, C; Read, P; Brazier, Jon; Jarvis, P; Chavda, Shyam; Bromley, T; Turner, A (2019-04-16)The first aim of the present study was to quantify and compare asymmetries among professional soccer and cricket athletes. The second aim was to examine the association between asymmetries and performance within both groups. ... -
Gene Variants Previously Associated with Reduced Soft Tissue Injury Risk: Part 1 – Independent Associations with Elite Status in Rugby
Brazier, Jon; Antrobus, M; Herbert, A; Callus, P; Stebbings, G; Day, S; Heffernan, S; Kilduff, L; Bennett, M; Erskine, R; Raleigh, Stuart; Collins, M.; Pitsiladis, Y; Williams, A (2022-03-29)There is growing evidence of genetic contributions to tendon and ligament pathologies. Given the high incidence and severity of tendon and ligament injuries in elite rugby, we studied whether 13 gene polymorphisms previously ... -
Gene variants previously associated with reduced soft-tissue injury risk: Part 2 – Polygenic associations with elite status in Rugby
Brazier, Jon; Antrobus, M; Herbert, A; Callus, P; Khanal, P; Stebbings, G; Day, S; Heffernan, S; Kilduff, L; Bennett, M; Erskine, R; Raleigh, Stuart; Collins, M.; Pitsiladis, Y; Williams, Alun G. (2022-12-26)Part 1 of this genetic association series highlighted several genetic variants independently associated with elite status in rugby. However, it is highly likely that the genetic influence on elite status is polygenic due ... -
Genetic Factors That Could Affect Concussion Risk in Elite Rugby
Antrobus, M; Brazier, Jon; Stebbings, G; Day, S; Heffernan, S; Kilduff, L; Erskine, R; Williams, A (2021-01-22)Elite rugby league and union have some of the highest reported rates of concussion (mild traumatic brain injury) in professional sport due in part to their full-contact high-velocity collision-based nature. Currently, ... -
An Investigation into Genetic Associations with Musculoskeletal Soft Tissue Injuries in Elite Rugby – Preliminary Findings
Brazier, Jon; Antrobus, M; Heffernan, S; Stebbings, G; Day, S; Hennis, P; Erskine, R; Kilduff, L; Williams, A (2017-03-11) -
Jumping-based Asymmetries are Negatively Associated with Jump, Change of Direction, and Repeated Sprint Performance, but not Linear Speed, in Adolescent Handball Athletes
Madruga, M; Bishop, Chris; Read, P.; Lake, Jason; Brazier, Jon; Romero-Rodriguez, Daniel (2020-01-31)The aim of the present study was to determine the association of multi-directional jumping asymmetries with measures of physical performance. Forty-two youth handball athletes (age: 16.0 ± 1.3 years; body height: 174.11 ± ... -
Magnitude or Direction? Seasonal Variation of Inter-limb Asymmetry in Elite Academy Soccer Players
Bishop, C; Read, P; Chavda, Shyam; Jarvis, P; Brazier, Jon; Bromley, T; Turner, A (2022-04-30)Previous research has highlighted a distinct lack of longitudinal data for asymmetry. The aims of the present study were to provide seasonal variation data for the magnitude and direction of asymmetry. Eighteen elite male ... -
Nutritional and Non-nutritional Strategies in Bodybuilding: Impact on Kidney Function
Tidmas, V; Brazier, Jon; Hawkins, Janine; Forbes, S; Bottoms, Lindsay; Farrington, Kenneth (2022-04-03)Bodybuilders routinely engage in many dietary and other practices purported to be harmful to kidney health. The development of acute kidney injury, focal segmental glomerular sclerosis (FSGS) and nephrocalcinosis may be ... -
Tendon and Ligament Injuries in Elite Rugby: The Potential Genetic Influence
Brazier, Jon; Antrobus, M; Stebbings, G; Day, S; Heffernan, S; Cross, M; Williams, A (2019-06-04)This article reviews tendon and ligament injury incidence and severity within elite rugby union and rugby league. Furthermore, it discusses the biological makeup of tendons and ligaments and how genetic variation may ...