Browsing Research publications by Author "Facer, Paul"
Now showing items 1-2 of 2
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Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons
Anand, Uma; Otto, William R; Sanchez-Herrera, Daniel; Facer, Paul; Yiangou, Yiangos; Korchev, Yuri; Birch, Rolfe; Benham, Christopher; Bountra, Chas; Chessell, Iain P; Anand, Praveen (2008)Cannabinoid receptor 2 (CB2) agonists provide the potential for treating chronic pain states without CNS effects associated with CB1 receptor activation. Animal models suggest that they act mainly via non-neuronal cells, ... -
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
Facer, Paul; Casula, Maria A; Smith, Graham D; Benham, Christopher D; Chessell, Iain P; Bountra, Chas; Sinisi, Marco; Birch, Rolfe; Anand, Praveen (2007)Transient receptor potential (TRP) receptors expressed by primary sensory neurons mediate thermosensitivity, and may play a role in sensory pathophysiology. We previously reported that human dorsal root ganglion (DRG) ...