Browsing Research publications by Author "Ghaemmaghami, Amir M."
Now showing items 1-4 of 4
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The development of a 3D immunocompetent model of human skin
Chau, David Y.S.; Johnson, Claire; MacNeil, Sheila; Haycock, John W.; Ghaemmaghami, Amir M. (2013-09)As the first line of defence, skin is regularly exposed to a variety of biological, physical and chemical insults. Therefore, determining the skin sensitization potential of new chemicals is of paramount importance from ... -
Laminin and Fibronectin Treatment Leads to Generation of Dendritic Cells with Superior Endocytic Capacity
Garcia-Nieto, Samuel; Johal, Ramneek K.; Shakesheff, Kevin M.; Emara, Mohamed; Royer, Pierre-Joseph; Chau, David Y.S.; Shakib, Farouk; Ghaemmaghami, Amir M. (2010-04-19)Background: Sampling the microenvironment at sites of microbial exposure by dendritic cells ( DC) and their subsequent interaction with T cells in the paracortical area of lymph nodes are key events for initiating immune ... -
Tissue transglutaminase (TG-2) modified amniotic membrane : a novel scaffold for biomedical applications
Chau, David Y.S.; Brown, Sheridan V.; Mather, Melissa L.; Hutter, Victoria; Tint, Naing L.; Dua, Harminder S.; Rose, Felicity R. A. J.; Ghaemmaghami, Amir M. (2012-08)The amniotic membrane (AM) is considered as a natural cell culture substrate and has occasionally been exploited in regenerative medicine especially for ocular surface reconstruction and dermal wound healing applications. ... -
Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype - implications for the role of transglutaminase in coeliac disease
Dalleywater, William J.; Chau, David Y.S.; Ghaemmaghami, Amir M. (2012-04-16)Dendritic cells (DCs) are part of the innate immune system with a key role in initiating and modulating T cell mediated immune responses. Coeliac disease is caused by inappropriate activation of such a response leading to ...