Browsing Research publications by Author "Gillan, Claire M."
Now showing items 1-3 of 3
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Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder
Gillan, Claire M.; Papmeyer, Martina; Morein-Zamir, Sharon; Sahakian, Barbara J.; Fineberg, Naomi; Robbins, Trevor W.; de Wit, Sanne (2011-07)Objective: Obsessive-compulsive disorder (OCD) is characterized by repetitive, ritualistic behaviors and thought patterns. Although patients with OCD report that these compulsive behaviors are unproductive and often ... -
Hyperconnectivity of the ventromedial prefrontal cortex in obsessive-compulsive disorder
Apergis-Schoute, Annemieke M; Bijleveld, Bastiaan; Gillan, Claire M.; Fineberg, Naomi; Sahakian, Barbara J. (2018-11-30)Neuroimaging research has highlighted maladaptive thalamo-cortico-striatal interactions in obsessive-compulsive disorder as well as a more general deficit in prefrontal functioning linked with compromised executive ... -
Mapping Compulsivity in the DSM-5 Obsessive Compulsive and Related Disorders : Cognitive Domains, Neural Circuitry, and Treatment
Fineberg, Naomi A.; Apergis-Schoute, Annemieke M.; Vaghi, Matilde M.; Banca, Paula; Gillan, Claire M.; Voon, Valerie; Chamberlain, Samuel R.; Cinosi, Eduardo; Reid, Jemma; Shahper, Sonia; Bullmore, Edward T.; Sahakian, Barbara J.; Robbins, Trevor W. (2018-01-01)Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm. Growing evidence suggests that the neurocognitive mechanisms mediating behavioral inhibition (motor inhibition, cognitive inflexibility) ...