Browsing Research publications by Author "Gu, Jingxia"
Now showing items 1-2 of 2
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Nano self-assemblies based on cholate grafted poly-L-lysine enhanced the solubility of sterol-like drugs
Gu, Jingxia; Cheng, Woei Ping; Hoskins, Clare; Lin, Paul Kong Thoo; Zhao, Lingling; Zhu, Lijun; Qu, Xiaozhong; Yang, Zhenzhong (2011)The physicochemical compatibility between amphiphilic polymers and hydrophobic drugs has been recognized as an important issue for improving the drug solubilisation in polymeric micelle formulations. In this work, poly-L-lysine ... -
pH-triggered reversible "stealth" polycationic micelles
Gu, Jingxia; Cheng, Woei Ping; Liu, Jiguang; Lo, Sum-Yee; Smith, David; Qu, Xiaozhong; Yang, Zhenzhong (2008-01)Amphiphilic polycations with a "stealth" cationic nature have been designed and synthesized by the PEGylation of polycationic amphiphile via a novel pH responsible benzoic imine linker. The linkage is stable in aqueous ...