Browsing Research publications by Author "Health Research Methods Unit"
Now showing items 1-20 of 116
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Adherence to prophylaxis in adolescents and young adults with severe haemophilia: A quantitative study with patients
Van Os, Sandra; Troop, Nicholas; Sullivan, Keith; Hart, Daniel (2017-01-19)Introduction: haemophilia is an inherited bleeding disorder caused by a deficiency in one of the blood coagulation factors. For people affected by severe haemophilia, the deficiency can cause spontaneous internal bleeding. ... -
Advances in Problematic Usage of the Internet Research – A Narrative Review by Experts from the European Network for Problematic Usage of the Internet
Fineberg, Naomi; Menchon, Josè M; Hall, Natalie; Dell'Osso, Bernardo; Brand, Matthias; Potenza, Marc; Chamberlain, Samuel R; Cirnigliaro, Giovanna; Lochner, Christine; Billieux, Joël; Demetrovics, Zsolt; Rumpf, Hans Jürgen; Muller, Astrid; Castro-Calvo, Jesús; Hollander, Eric; Burkauskas, Julius; Grünblatt, Edna; Walitza, Susanne; Corazza, Ornella; King, Daniel L; Stein, Dan J.; Grant, Jon E; Pallanti, Stefano; Bowden-Jones, Henrietta; Van Ameringen, Michael; Ioannidis, Konstantinos; Carmi, Lior; Goudriaan, Anna E; Martinotti, Giovanni; Sales, Celia M; Jones, Julia; Gjoneska, Biljiana; Király, Orsolya; Benatti, Beatrice; Vismara, Matteo; Pellegrini, Lucas; Conti, Dario; Cataldo, Ilaria; Riva, Gianluigi M; Yücel, Murat; Flayelle, Maèva; Hall, Thomas; Griffiths, Morgan; Zohar, Joseph (2022-10-30)Global concern about problematic usage of the internet (PUI), and its public health and societal costs, continues to grow, sharpened in focus under the privations of the COVID-19 pandemic. This narrative review reports the ... -
Antidepressant Usage in Haemodialysis Patients: Evidence of Sub-optimal Practice Patterns
Guirguis, Ayman; Almond, Michael; Chilcot, Joseph; Davenport, A.; Wellsted, David; Farrington, Kenneth (2020-06-01)Background: Depression is common in patients on haemodialysis and associated with adverse outcomes. Antidepressant use is widespread though evidence of efficacy is limited. Objectives: To study antidepressant management ... -
Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation
Spinthakis, Nikolaos; Gue, Ying X.; Farag, Mohamed; Srinivasan, Manivannan; Wellsted, David; Lip, Gregory Y H; Arachchillage, Deepa RJ; Gorog, Diana (2019-09-01)AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which strongly relates to improved functional outcome. The impact of oral anticoagulants ... -
Approaches to the identification and management of depression in people living with chronic kidney disease : A scoping review of 860 papers
Pearce, Christina J.; Hall, Natalie; Hudson, Joanna L.; Farrington, Ken; Tucker, Madeleine J. Ryan; Wellsted, David; Jones, Julia; Sharma, Shivani; Norton, Sam; Ormandy, Paula; Palmer, Nick; Quinnell, Anthony; Fitzgerald, Lauren; Griffiths, Sophie; Chilcot, Joseph (2023-01-16)Background: Depression is prevalent across the spectrum of Chronic Kidney Disease and associated with poorer outcomes. There is limited evidence regarding the most effective interventions and care pathways for depression ... -
ASSIST Trauma Care: Guiding Young Minds : Feasibility and pilot study report
Adler, Joanna R; McSweeney, Tim; Cresswell, Caroline; Wellsted, David; Hall, Natalie; Busby, Amanda; Littlechild, Brian (Youth Endowment Fund, 2023-07-28)Executive summary The project The Guiding Young Minds (GYM) programme aims to support young people with experience of trauma to improve potentially challenging behaviour, establish a vision of a positive future, and set ... -
The association between social deprivation and disease activity in rheumatoid arthritis: A systematic literature review
Dey, Mrinalini; Busby, Amanda; Ewell, Helen; Lempp, Heidi; Pratt, Arthur; Young, Adam; Isaacs, John; Nikiphorou, Elena (2022-04-21)Physical and mental illnesses are driven by ethnicity, social, environmental and economic determinants. Novel theoretical frameworks in rheumatoid arthritis (RA) focus on links and adverse interactions between and within ... -
Care pathways for the identification and management of depression in patients with chronic kidney disease: a rapid scoping review
Hall, Natalie; Pearce, Christina; Hudson, Joanna; Farrington, Kenneth; Wellsted, David; Jones, Julia; Sharma, Shivani; Norton, Sam; Ormandy, Paula; Palmer, Nick; Chilcot, Joe (2021-11-11)Depression is highly prevalent across the spectrum of Chronic Kidney Disease (CKD) and related to poor clinical outcomes. There is limited evidence regarding the most effective and acceptable interventions to manage ... -
Changes to Physical Activity, Sitting Time, Eating Behaviours and Barriers to Exercise during the First COVID-19 ‘Lockdown’ in an English Cohort
Kass, Lindsy; Desai, Terun; Sullivan, Keith; Muniz, Daniel; Wells, Amy (2021-09-24)This study aimed to determine the effect of the first English national COVID-19 lockdown on physical activity (PA), sitting time, eating behaviours and body mass in an adult cohort. This was further examined to determine ... -
Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis
Toutountzidis, Diamantis; Gale, Tim M.; Irvine, Karen; Sharma, Shivani; Laws, Keith R. (2022-06-29)The association of early life adversities and psychosis symptoms is well documented in clinical populations; however, whether this relationship also extends into subclinical psychosis remains unclear. In particular, are ... -
Citizen Consultation on Problematic Usage of the Internet: Ethical Considerations and Empirical Insights from Six Countries
Gjoneska, Biljana; Jones, Julia; Vella, Anna Maria; Bonanno, Philip; Flora, Katerina; Fontalba-Navas, Andres; Hall, Natalie; Ignjatova, Liljana; Kirtava, Zviad; Moreno Sanjuan, Daniel; Piedade Vaz-Rebelo, Maria; Sales, Celia M (2021-04-01)Scientists and citizens can work together to improve the collective well-being, if citizens are inspired to help the advancement of science, and researchers motivated to listen to the voices of citizens. The benefits of ... -
Commentary on the article: “Maintenance of Wellness in Patients With Obsessive-Compulsive Disorder Who Discontinue Medication After Exposure/Response Prevention Augmentation A Randomized Clinical Trial”
Fineberg, Naomi; Hollander, Eric; Grant, Jon E; Chamberlain, Samuel R; Drummond, Lynne; Pellegrini, Luca; Laws, Keith; Wellsted, David; Reid, Jemma; Nezgovorova, Vera; Baldwin, David (2022-06-01) -
A Comparison of the Epidemiological Characteristics Between Influenza and COVID-19 Patients: A Retrospective, Observational Cohort Study.
Naji, Omar; Darwish, Iman; Bessame, Khaoula; Vaghela, Tejal; Hawkins, Anja; Elsakka, Mohamed; Merai, Hema; Lowe, Jeremy; Schechter, Miriam; Moses, Samuel; Busby, Amanda; Sullivan, Keith; Wellsted, David; Zamir, Muhammad; Kandil, Hala (2023-11-23)Background and objective It is crucial to make early differentiation between coronavirus disease 2019 (COVID-19) and seasonal influenza infections at the time of a patient's presentation to the emergency department (ED). ... -
Contributions of treatment centre and patient characteristics to patient-reported experience of haemodialysis: A national cross-sectional study
Hawkins, Janine; Smeeton, Nigel; Busby, Amanda; Wellsted, David; Rider, Beth; Jones, Julia; Steinkamp, Retha; Stannard, Catherine; Gair, Rachel; Van Der Veer, Sabine; Corps, Claire; Farrington, Kenneth (2021-04-14)OBJECTIVES: To examine the relative importance of patient and centre level factors in determining self-reported experience of care in patients with advanced kidney disease treated by maintenance haemodialysis (HD). DESIGN: ... -
Definition, assessment and management of frailty for people with intellectual disabilities: A scoping review.
Grohmann, Dominique; Wellsted, David; Mengoni, Silvana (2024-05)Background: People with intellectual disabilities may experience frailty earlier than the general population. This scoping review aimed to investigate how frailty is defined, assessed, and managed in adults with an ... -
Development of the Paranormal and Supernatural Beliefs Scale using classical and modern test theory
Dean, Charlotte E; Akhtar, Shazia; Gale, Tim M; Irvine, Karen; Wiseman, Richard; Laws, Keith R (2021-06-23)Background: This study describes the construction and validation of a new scale for measuring belief in paranormal phenomena. The work aims to address psychometric and conceptual shortcomings associated with existing ... -
Differential effects of sertraline and cognitive behavioural therapy on behavioural inhibition in patients with obsessive compulsive disorder
Reid, Jemma E; Pellegrini, Luca; Drummond, Lynne; Varlakova, Yana; Shahper, Sonia; Baldwin, David S; Manson, Christopher; Chamberlain, Samuel R; Robbins, Trevor W; Wellsted, David; Fineberg, Naomi A (2024-04-25)Patients with obsessive compulsive disorder (OCD) randomised to sertraline, manualised cognitive behavioural therapy (CBT), or combination (sertraline + CBT), underwent cognitive assessment. Cognitive testing was conducted ... -
Do people with intellectual disabilities understand their prescription medication? A scoping review
Smith, Megan; Adams, Danielle; Carr, Claudia; Mengoni, Silvana (2019-11-01)Background: People with intellectual disabilities are more likely to experience poor health than the general population and are frequently prescribed multiple medications. Therefore, it is important that people with ... -
Effect of Transdermal Magnesium Cream on Serum and Urinary Magnesium Levels in Humans: A Pilot Study
Kass, Lindsy; Rosanoff, Andrea; Tanner, Amy; McAuley, William; Sullivan, Keith; Plesset, Michael (2017-04-12)Background Oral magnesium supplementation is commonly used to support a low magnesium diet. This investigation set out to determine whether magnesium in a cream could be absorbed transdermally in humans to improve magnesium ...