Browsing Research publications by Author "Kirton, S.B."
Now showing items 1-1 of 1
-
Impact of incorporating the 2C5 crystal structure into comparative models of cytochrome P450 2D6
Kirton, S.B.; Sutcliffe, M.J.; Kemp, C.A.; Tomkinson, N.P.; St-Gallay, S. (2002-11-01)Cytochrome P450 2D6 (CYP2D6) metabolizes approximately one third of the drugs in current clinical use. To gain insight into its structure and function, we have produced four different sets of comparative models of 2D6: one ...