Browsing Research publications by Author "Lian, Lu-Yun"
Now showing items 1-4 of 4
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Characterisation of the interaction of the C-terminus of the dopamine D2 receptor with neuronal calcium sensor-1
Lian, Lu-Yun; Pandalaneni, Sravan R.; Patel, Pryank; McCue, Hannah V.; Haynes, Lee P.; Burgoyne, Robert D. (2011-11-16)NCS-1 is a member of the neuronal calcium sensor (NCS) family of EF-hand Ca(2+) binding proteins which has been implicated in several physiological functions including regulation of neurotransmitter release, membrane ... -
Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion
Patel, Pryank; Clarke, Christopher; Barraclough, Dong Liu; Jowitt, Thomas Adam; Rudland, Philip Spencer; Barraclough, Roger; Lian, Lu-Yun (2013-03-11)Anterior gradient 2 (AGR2) is a normal endoplasmic reticulum protein that has two important abnormal functions, amphibian limb regeneration and human cancer metastasis promotion. These normal intracellular and abnormal ... -
Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch
Patel, Pryank; Prescott, Gerald R.; Burgoyne, Robert D; Lian, Lu-Yun; Morgan, Alan (2016-07-21)Cysteine string protein (CSP) is a member of the DnaJ/Hsp40 chaperone family that localizes to neuronal synaptic vesicles. Impaired CSP function leads to neurodegeneration in humans and model organisms as a result of ... -
Solution NMR structure of the Ca2+-bound N-terminal domain of CaBP7 : a regulator of golgi trafficking
McCue, Hannah V.; Patel, Pryank; Herbert, Andrew P.; Lian, Lu-Yun; Burgoyne, Robert D.; Haynes, Lee P. (2012-11-02)Calcium-binding protein 7 (CaBP7) is a member of the calmodulin (CaM) superfamily that harbors two high affinity EF-hand motifs and a C-terminal transmembrane domain. CaBP7 has been previously shown to interact with and ...