Browsing Research publications by Author "Loi, Barbara"
Now showing items 1-13 of 13
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4,4’-dimethylaminorex (‘4,4’-DMAR’; ‘Serotoni’) misuse; a web-based study
Loi, Barbara; Zloh, Mire; Antonietta, Maria; Corkery, John; Schifano, Fabrizio (2017-06-28)Background: 4,4′-DMAR (4,4’-dimethylaminorex; ‘Serotoni’) is a potent stimulant drug which has recently been associated with a number of fatalities in Europe. Over the last few years, online communities have emerged as ... -
Deaths in the Lesbian, Gay, Bisexual and Transgender United Kingdom communities associated with GHB and precursors
Corkery, John M; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Schifano, Fabrizio (2017-11-08)Background Misuse of gammahydroxybutrate (GHB) and its prodrugs gammabutyrolactone (GBL) and 1,4 butanediol (1,4-BD) has increased greatly since the early 1990s, particularly amongst lesbian, gay, bisexual and transgender ... -
Deaths of individuals aged 16-24 years in the UK after using mephedrone
Loi, Barbara; Corkery, John; Claridge, Hugh; Goodair, Christine; Chiappini, Stephania; Gimeno Clemente, Carla; Schifano, Fabrizio (2015-07-28)Objective: Mephedrone is a stimulant drug chemically related to amphetamine, with effects similar to those of amphetamine and cocaine. This study aims to analyse fatalities following ingestion of mephedrone in the UK amongst ... -
Drug-related deaths in the UK: January-December 2012 : Annual report 2013
Corkery, John; Claridge, Hugh; Loi, Barbara; Goodair, Christine; Schifano, Fabrizio (International Centre for Drug Policy, 2014-02-12)Drug-related deaths reported by Coroners in England, Wales, Northern Ireland, Guernsey, Jersey and the Isle of Man; Police forces in Scotland; & the Northern Ireland Statistics and Research Agency -
The evolution and characteristics of UK deaths involving GHB and its analogues
Corkery, John; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Corazza, Ornella; Elliott, Simon; Schifano, Fabrizio (2014-03)Introduction: misuse of gamma hydroxybutyrate (GHB) and gamma butyrolactone (GBL) increased in Western countries from the early 1990s. The period since has seen a rising numbers of deaths. This presentation outlines the ... -
Fatalities Associated with Mephedrone in Combination with Other Stimulant Drugs in Young People Aged 16-24 Years
Loi, Barbara; Chiappini, Stephania; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Schifano, Fabrizio (2013-12)Introduction: Mephedrone is a stimulant Class B drug chemically related to amphetamine. It comes in tablet or powder form and has no therapeutic use. Mephedrone’s reported effects are similar to those of amphetamine and ... -
Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4 butanediol (1,4-BD; BDO) : a literature review with a focus on UK fatalities related to non-medical use
Corkery, John; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Corazza, Ornella; Elliott, Simon; Schifano, Fabrizio (2015-06)Misuse of gamma hydroxybutrate (GHB) and gamma butyrolactone (GBL) has increased greatly since the early 1990s, being implicated in a rising number of deaths. This paper reviews knowledge on GHB and derivatives, and explores ... -
Methoxetamine-related deaths in the UK : an overview
Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2015-07-28)Objective: The goal of this study is to provide an update on the data given on methoxetamine (MXE)-related fatalities that occurred in 2011–2013, presented at the Second International Conference on Novel Psychoactive ... -
Methoxetamine: An Analogue of Ketamine
Chiappini, Stephania; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2013-12)Introduction: Methoxetamine acts similarly to a non-competitive antagonist at the N-methyl-aspartate receptor and a Dopamine reuptake inhibitor. Its behavioural effects resemble those induced by dissociative anesthetics, ... -
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids : BB-22, 5F-PB-22, 5F-AKB-48 and STS-135
De Luca, Maria Antonietta; Castelli, M. Paola; Loi, Barbara; Porcu, Alessandra; Martorelli, Mariella; Miliano, Cristina; Kellett, Kathryn; Davidson, Colin; Stair, Jacqueline L.; Schifano, Fabrizio; Di Chiara, Gaetano (2016-06-01)In order to investigate the in vivo dopamine (DA) stimulant properties of selected 3rd generation Spice/K2 cannabinoids, BB-22, 5F-PB-22, 5F-AKB-48 and STS-135, their in vitro affinity and agonist potency at native rat and ... -
‘Special M’ related fatalities in the UK.
Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2014-03)Introduction: methoxetamine (MXE; ‘special M’) is a novel psychoactive substance that first appeared in 2010 as a legal alternative to ketamine and, despite now being a Class B drug, is still widely marketed via the internet ... -
UK deaths associated with ‘Z’ drugs (Zopiclone, Zolpidem & Zaleplon)
Casula, Salvatore; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (Advisory Council on the Misuse of Drugs, 2013-09-05) -
The Unregulated Psychoactive Compound: ‘Benzo Fury’
Gimeno Clemente, Carla; Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2013-12)Introduction: The ‘legal high’ ‘Benzo Fury’ [1-(benzofuran-5-yl)propan-2-amine (5-APB) and 1-(benzofuran-6-yl)propan-2-amine (6-APB)] is an unregulated psychoactive compound which has similar effects as known controlled ...