Browsing Research publications by Author "Mekky, Radwa Y."
Now showing items 1-2 of 2
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A Novel Epigenetic Strategy to Concurrently Block Immune Checkpoints PD-1/PD-L1 and CD155/TIGIT in Hepatocellular Carcinoma
Assal, Reem A.; Elemam, Noha M.; Mekky, Radwa Y.; Attia, Abdelrahman A.; Soliman, Aya Hesham; Gomaa, Asmaa Ibrahim; Efthimiadou, Eleni K.; Braoudaki, Maria; Fahmy, Sherif Ashraf; Youness, Rana A. (2024-04-17)Tumor microenvironment is an intricate web of stromal and immune cells creating an immune suppressive cordon around the tumor. In hepatocellular carcinoma (HCC), Tumor microenvironment is a formidable barrier towards novel ... -
Pharmacogenomic and epigenomic approaches to untangle the enigma of IL-10 blockade in oncology
Elemam, Noha M.; Mekky, Radwa Y.; Rashid, Gowhar; Braoudaki, Maria; Youness, Rana A. (2024-01-08)The host immune system status remains an unresolved mystery among several malignancies. An immune-compromised state or smart immune-surveillance tactics orchestrated by cancer cells are the primary cause of cancer invasion ...