Browsing Research publications by Author "Mulder, Hindrik"
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Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production
Knudsen, Jakob G; Hamilton, Alexander; Ramracheya, Reshma; Tarasov, Andrei I; Brereton, Melissa; Haythorne, Elizabeth; Chibalina, Margarita V; Spégel, Peter; Mulder, Hindrik; Zhang, Quan; Ashcroft, Frances M; Adam, Julie; Rorsman, Patrik (2019-02-05)Diabetes is a bihormonal disorder resulting from combined insulin and glucagon secretion defects. Mice lacking fumarase (Fh1) in their β cells (Fh1βKO mice) develop progressive hyperglycemia and dysregulated glucagon ...