Browsing Research publications by Author "Ostovar, Mehrnoosh"

Now showing items 1-4 of 4

    • Bicyclic 6-6 Systems: Pteridines 

      Rossiter, Sharon; Ostovar, Mehrnoosh (Elsevier, 2022)
      This article describes the literature on pteridines, covering the period from 2008 to 2020. The physical properties and reactions include photochemistry, substitution at ring nitrogens, nucleophilic substitution at ring ...

    • Discovery of novel small molecule inhibitors of S100P, with in vitro anti-metastatic effects on pancreatic cancer cells 

      Camara, Ramatoulie; Ogbeni, Deborah; Gerstmann, Lisa; Ostovar, Mehrnoosh; Hurer, Ellie; Scott, Mark; Mahmoud, Nasir; Radon, Tomasz; Crnogorac-Jurcevic, Tatjana; Patel, Pryank; Mackenzie, Louise Susan; Chau, David; Kirton, Stewart; Rossiter, Sharon (2020-10-01)
      S100P, a calcium- binding protein, is known to advance tumor progression and metastasis in pancreatic and several other cancers. Herein is described the in silico identification of a putative binding pocket of S100P to ...

    • Enantioselective Synthesis of the Cyclopiazonic Acid Family Using Sulfur Ylides 

      Zhurakovskyi, Oleksandr; Türkmen, Yunus E; Löffler, Lorenz E; Moorthie, Vijayalakshmi A; Chen, C Chun; Shaw, Michael A; Crimmin, Mark R; Ferrara, Marco; Ahmad, Mushtaq; Ostovar, Mehrnoosh; Matlock, Johnathan V; Aggarwal, Varinder K (2018-01-26)
      A convergent, nine-step (LLS), enantioselective synthesis of α-cyclopiazonic acid and related natural products is reported. The route features a) an enantioselective aziridination of an imine with a chiral sulfur ylide; ...

    • Evaluating academic answers generated using ChatGPT 

      Fergus, Suzanne; Botha, Michelle; Ostovar, Mehrnoosh (2023-04-11)
      The integration of technology in education has become ever more prioritized since the COVID-19 pandemic. Chat Generative Pre-Trained Transformer (ChatGPT) is an artificial intelligence technology that generates conversational ...