Browsing Research publications by Author "Sansom, M. S. P."
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Exploring models of the influenza A M2 channel: MD simulations in a phospholipid bilayer
Forrest, L. R.; Kukol, A.; Arkin, I.T.; Tieleman, D. P.; Sansom, M. S. P. (2000-01)The M2 protein of influenza A virus forms homotetrameric helix bundles, which function as proton-selective channels. The native form of the protein is 97 residues long, although peptides representing the transmembrane ... -
The structure of the HIV-1 Vpu ion channel: modelling and simulation studies
Cordes, F. S.; Kukol, A.; Forrest, L. R.; Arkin, I.T.; Sansom, M. S. P.; Fischer, W. B. (2001-06-06)Vpu is an 81 amino acid auxiliary protein in HIV-1 which exhibits channel activity. We used two homo-pentameric bundles with the helical transmembrane segments derived from FTIR spectroscopy in combination with a global ...