Browsing Research publications by Author "Wade, John"
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Mathematical Modeling of PI3K/Akt Pathway in Microglia
Poshtkohi, Alireza; Wade, John; McDaid, Liam; Liu, Junxiu; L Dallas, Mark; Bithell, Angela (2024-03-21)The motility of microglia involves intracellular signaling pathways that are predominantly controlled by changes in cytosolic Ca 2+ and activation of PI3K/Akt (phosphoinositide-3-kinase/protein kinase B). In this letter, ... -
Synchrony : A spiking-based mechanism for processing sensory stimuli
Glackin, Cornelius; Maguire, Liam; McDaid, Liam; Wade, John (2012)Synchronous behaviour of neurons is both beneficial and detrimental to the neural code. On the one extreme, synchronous firing activity is well known to be a symptom of epileptic seizures, whilst on the other synchrony ...