Browsing Research publications by Author "Winocour, P."
Now showing items 1-4 of 4
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Are low erythropoietin and 1,25-dihydroxyvitamin D levels indicative of tubulo-interstitial dysfunction in diabetes without persistent microalbuminuria?
Singh, D.K.; Winocour, P.; Summerhayes, B.; Viljoen, A.; Sivakumar, G.; Farrington, Ken (2009)Aims: To investigate the relationship between Erythropoietin (EPO) and 1,25-dihydroxyvitamin D levels, and tubular damage in patients with diabetes mellitus (DM) without persistent microalbuminuria. Methods: We measured ... -
Low serum osteoprotegerin levels in normoalbuminuric type 1 diabetes mellitus
Singh, D.K.; Winocour, P.; Summerhayes, B.; Viljoen, A.; Sivakumar, G.; Farrington, Ken (2010)The aim of this study is to establish whether abnormal mineral metabolism is present in patients with type 1 DM with normal renal function and in the absence of microalbuminuria. Serum levels of 1,25-dihydroxyvitamin D, ... -
Mechanisms of disease : the hypoxic tubular hypothesis of diabetic nephropathy
Singh, D.K.; Winocour, P.; Farrington, Ken (2008)Diabetic nephropathy is traditionally considered to be a primarily glomerular disease, although this contention has recently been challenged. Early tubular injury has been reported in patients with diabetes mellitus whose ... -
Oxidative stress in early diabetic nephropathy : fuelling the fire
Singh, D.K.; Winocour, P.; Farrington, Ken (2011)Diabetic nephropathy is a major microvascular complication of diabetes mellitus and the most common cause of end-stage renal disease worldwide. The treatment costs of diabetes mellitus and its complications represent a ...