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Now showing items 131-140 of 157
An investigation into the in vivo performance variability of pH responsive polymers for ileo-colonic drug delivery using gamma scintigraphy in humans
(2006-12)
Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous ...
Is there a difference between the ability to kneel after unilateral and bilateral total knee replacement?
(2006)
This study investigates the difference between the ability to kneel in patients after unilateral and bilateral total knee replacement. We used the Oxford knee questionnaire to assess knee function, and an additional question ...
Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology
(2006)
For the majority of Duchenne muscular dystrophy (DMD) mutations, antisense oligonucleotide (AON)-mediated exon skipping has the potential to restore a functional protein. Here we show that weekly intravenous injections of ...
Sensing of lysophospholipids by TRPC5 calcium channel
(2006)
TRPC calcium channels are emerging as a ubiquitous feature of vertebrate cells, but understanding of them is hampered by limited knowledge of the mechanisms of activation and identity of endogenous regulators. We have ...
Derivation and validation of a new global method for assessing nutritional status in patients with cirrhosis
(2006)
Accurate assessments of nutritional status are difficult to obtain in patients with cirrhosis. The aim of this study was to devise and validate a global nutritional assessment scheme for use in this patient population. ...
Randomized controlled trial of specific spinal stabilization exercises and conventional physiotherapy for recurrent low back pain
(2006)
Pragmatic, multicentered randomized controlled trial, with 12-month follow-up.
Postural differences in the shoulder girdle during normal locomotion in treadmill vs. over ground walking
(IOS Press, 2006)
In a clinical setting, most musculoskeletal assessment related to gait is undertaken using a treadmill which is additionally widely used during gait and neurological rehabilitation. Although previous studies have reported ...
Two-component models are of limited value for the assessment of body composition in patients with cirrhosis
(2006)
Most techniques for measuring body composition are based on 2-component models (2-CMs) and depend on assumptions relating to the constancy of the density (D(FFM)) and hydration fraction (HF(FFM)) of fat-free mass (FFM).
Buprenorphine mortality, seizures and prescription data in the UK, 1980-2002
(2005)
Buprenorphine safety in overdose has been debated recently, but no mortality data related to this compound from the UK have been published. To gather together all of the buprenorphine mortality figures, a number of different ...
An association between respiratory function and hip bone mineral density in older men: a cross-sectional study
(2005)
The association between respiratory function and bone mineral density (BMD) among women living in the community has been reported previously. We examined the association between forced expiratory volume in 1 s (FEV(1)) and ...