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Microvesicles and epithelial mesenchymal transition in the development of cancer
(2012-09-13)
Microvesicles released by tumour cell lines are thought to play an important role in both extracellular matrix (ECM) invasion and evasion of the immune system. We have examined the role of MVs derived from a T cell line ...
Human skeletal muscle derived microvesicles induce apoptosis in highly metastatic prostate cancer cells
(2012-09-13)
The human skeletal muscle is a highly vascularised tissue that contributes approximately 40% of the total body mass. These two factors make it a prime target for secondary cancer metastases. Surprisingly, malignant cancers ...
Cancer cell expulsion of anticancer drugs through shedding of microvesicles: association with drug resistance and tumour survival
(2012-09-13)
Microvesicles (MVs) are small (0.1-≤1 µm in diameter) heterogeneous vesicles released from cells constitutively or upon activation, that mediate intercellular communication. Multi-drug resistance (MDR) has been defined as ...