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Parenclitic and Synolytic Networks Revisited
(2021-10-20)
Parenclitic networks provide a powerful and relatively new way to coerce multidimensional data into a graph form, enabling the application of graph theory to evaluate features. Different algorithms have been published for ...
Multi-marker longitudinal algorithms incorporating HE4 and CA125 in ovarian cancer screening of postmenopausal women
(2020-07)
Longitudinal CA125 algorithms are the current basis of ovarian cancer screening. We report on longitudinal algorithms incorporating multiple markers. In the multimodal arm of United Kingdom Collaborative Trial of Ovarian ...
The Human Body as a Super Network : Digital Methods to Analyze the Propagation of Aging
(2020-05-25)
Biological aging is a complex process involving multiple biological processes. These can be understood theoretically though considering them as individual networks—e.g., epigenetic networks, cell-cell networks (such as ...
Improved early detection of ovarian cancer using longitudinal multimarker models
(2020-03-17)
Background: Ovarian cancer has a poor survival rate due to late diagnosis and improved methods are needed for its early detection. Our primary objective was to identify and incorporate additional biomarkers into longitudinal ...
Expanding TREC and KREC Utility in Primary Immunodeficiency Diseases Diagnosis
(2020-03-03)
Primary immunodeficiency diseases (PID) area heterogeneous group of disorders caused by genetic defects of the immune system, which manifest clinically as recurrent infections, autoimmune diseases or malignancies. Early ...