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Cloning and functional expression of a human orthologue of the rat vanilloid receptor-1
(2000-11-01)
Capsaicin, resiniferatoxin, protons or heat have been shown to activate an ion channel, termed the rat vanilloid receptor-1 (rVR1), originally isolated by expression cloning for a capsaicin sensitive phenotype. Here we ...
Rank-order inhibition by ω-conotoxins in human and animal autonomic nerve preparations
(2000)
The inhibitory effects of the ω-conotoxins GVIA, MVIIA and MVIIC on electrically-evoked, tetrodotoxin (10−7 M)-sensitive, autonomic nerve activity were studied using human, rat or guinea-pig vas deferens and intestinal ...