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Use of benzylglycinamide by a HIV-seropositive polysubstance user: : the changing pattern of novel psychoactive substance use among youths
(2016-09-30)
A 24-year old woman with multisubstance use since the age of 13, including opioids and cocaine, and long-standing HIV/HCV seropositivity status, presented with psychosis, agitation, and insomnia at the emergency department ...
Substance use and misuse - Legal highs
(Centre for Pharmacy Post Graduate Education (CPPE), 2016-09-21)
This is an update to the online course on substance misuse designed for post-graduate pharmacists. The update was reviewed by Public Health England and the CPPE. It was published by the CPPE in Sep 2016. It is accessed by ...
Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens
(2016-07-02)
There are increasing levels of concern relating to the rapidly evolving novel psychoactive substances/NPS and web markets’ scenarios. The paper aims at providing an overview of the clinical pharmacological issues related ...
A Decade of Gabapentinoid Misuse: : An Analysis of the European Medicines Agency’s ‘Suspected Adverse Drug Reactions’ Database
(2016-06-16)
Introduction: The gabapentinoids pregabalin and gabapentin are being increasingly prescribed for a range of clinical conditions. Recently, although gabapentinoids at therapeutic dosages may present with low addictive ...
NPS: Medical Consequences Associated with Their Intake
(Springer Nature, 2016-06-07)
Over the last decade, the 'traditional' drug scene has been supplemented - but not replaced - by the emergence of a range of novel psychoactive substances (NPS), which are either newly created or existing drugs, including ...
Gli Psiconauti: navigatori della mente o sperimentatori chimici?
(2016-06-01)
Recentemente, all’interno delle comunità online (forum, blog, social network), si sta diffondendo una nuova generazione di consumatori di sostanze, altamente informati ed esperti nel campo delle nuove sostanze psicoattive ...
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids : BB-22, 5F-PB-22, 5F-AKB-48 and STS-135
(2016-06-01)
In order to investigate the in vivo dopamine (DA) stimulant properties of selected 3rd generation Spice/K2 cannabinoids, BB-22, 5F-PB-22, 5F-AKB-48 and STS-135, their in vitro affinity and agonist potency at native rat and ...
The consequences of drug misuse on post-marketing surveillance
(2016-04-25)
Over the past decade, the ‘traditional’ drug scenario has shown significant changes because of the emergence of a range of molecules, e.g. the novel psychoactive substances (NPS), which are either already existing or newly ...