Now showing items 11-20 of 64
Evidence for flocculation-controlled microcrystallisation of salmeterol xinafoate
The therapeutic management of pulmonary disease depends upon the efficient delivery of aerosolized drug particles with an aerodynamic diameter of 2.5–6 mm (Pritchard 2001). Particles for such aerosols are routinely produced ...
Determination of the diffusion coefficient of cyanophenol in carbosil membrane using ATR-FTIR spectroscopy
Model membranes are often used in place of human skin when evaluating dermal drug delivery systems. This is because they offer several advantages compared with human epidermis including their ready availability, uniformity ...
Sequence of RNA-dependent RNA polymerase genes provides evidence for three more distinct mitoviruses in Ophiostoma novo-ulmi isolate Ld
Three of the twelve double-stranded (ds) RNAs, dsRNAs 1a, 1b and 3b, which are located in the mitochondria of a diseased isolate, Ld, of the Dutch elm disease fungus, Ophiostoma novo-ulmi have been cDNA cloned and sequenced. ...
Postgraduate education for advanced practitioners : a novel approach to course design
Describes a new approach to developing learning to support advanced practitioner development which builds on the positive experiences of how adults learn, education theory, clinical practice and peer review
Schistosome cercarial interactions with human keratinocytes and langerhans cells
The human parasite, Schistosoma mansoni is known to modulate host immune responses in order to promote its own survival. However, studies investigating the interaction between the skin-invading cercarial stage and cells ...
SkelGen : a general tool for structure-based de novo ligand design
The recent lapse in productivity in the pharmaceutical industry has facilitated the emergence of experimental and in silico structure-based design methodologies, based on identification of biologically active low molecular ...
NK1 antagonists based on seven membered lactam scaffolds
A new class of high affinity hNK(1)R antagonists based on seven-membered ring cores has been identified. This series, with relatively simple, compact structures, includes compounds with high affinity, good selectivity, and ...
Resistance to Leptosphaeria maculans (phoma stem canker) in Brassica napus (oilseed rape) induced by Leptosphaeria biglobosa and chemical defence activators in field and controlled environments
Effects of pretreatment of Brassica napus leaves with ascospores of Leptosphaeria biglobosa or chemical defence activators [acibenzolar-S-methyl (ASM) or menadione sodium bisulphite (MSB)] on infection by ascospores of ...
The effect of coloured overlays on reading ability in children with autism
Abnormalities of colour perception in children with autistic spectrum disorders have been widely reported anecdotally. However, there is little empirical data linking difficulties in colour perception with academic ...
Relationships between insect pests and their parasitoids in a winter oilseed rape crop
Studies of trophic and spatio-temporal relationships among invertebrates in crops are key to the identification of agents that have potential in biological control, and could enable modification of crop agronomy, such as ...