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Sertraline Versus Placebo in Patients with Major Depressive Disorder Undergoing Hemodialysis : A Randomized, Controlled Feasibility Trial
(2017-02-07)
BACKGROUND AND OBJECTIVES: Depression is common in patients on hemodialysis, but data on the benefits and risks of antidepressants in this setting are limited. We conducted a multicenter, randomized, double-blind, ...
A single weekly Kt/Vurea target for peritoneal dialysis patients does not provide an equal dialysis dose for all
(2016-12-31)
Dialysis adequacy is traditionally based on urea clearance, adjusted for total body volume (Kt/Vurea), and clinical guidelines recommend a Kt/Vurea target for peritoneal dialysis. We wished to determine whether adjusting ...
Exploring access to end of life care for ethnic minorities with end stage kidney disease through recruitment in action research
(2016-07-11)
BACKGROUND: Variation in provision of palliative care in kidney services and practitioner concerns to provide equitable access led to the development of this study which focussed on the perspectives of South Asian patients ...
Quality of Life and Physical Function in Older Patients on Dialysis : A Comparison of Assisted Peritoneal Dialysis with Hemodialysis
(2016-03-07)
BACKGROUND AND OBJECTIVES: In-center hemodialysis (HD) is often the default dialysis modality for older patients. Few centers use assisted peritoneal dialysis (PD), which enables treatment at home. This observational study ...
The mortality and hospitalization rates associated with the long interdialytic gap in thrice-weekly hemodialysis patients
(2015-09-30)
Excess mortality and hospitalization have been identified after the 2-day gap in thrice-weekly hemodialysis patients compared with 1-day intervals, although findings vary internationally. Here we aimed to identify factors ...
Understanding by older patients of dialysis and conservative management for chronic kidney failure
(2015-03-01)
BACKGROUND: Older adults with chronic kidney disease stage 5 may be offered a choice between dialysis and conservative management. Few studies have explored patients' reasons for choosing conservative management and none ...
Patients' and carers' experiences of interacting with home haemodialysis technology: implications for quality and safety
(2014-12-11)
BACKGROUND: Little is known about patients' and carers' experiences of interacting with home haemodialysis (HHD) technology, in terms of user experience, how the design of the technology supports safety and fits with home ...
Disease-specific predictive formulas for energy expenditure in the dialysis population
(2014-04-28)
OBJECTIVE: Metabolic rate is poorly understood in advanced kidney disease because direct measurement is expensive and time-consuming. Predictive equations for resting energy expenditure (REE) are needed based on simple ...
Energy metabolism, body composition, and urea generation rate in hemodialysis patients
(2013-10-01)
Hemodialysis (HD) adequacy is currently assessed using normalized urea clearance (Kt/V), although scaling based on Watson volume (V) may disadvantage women and men with low body weight. Alternative scaling factors such as ...