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Human skeletal muscle derived microvesicles induce apoptosis in highly metastatic prostate cancer cells
The human skeletal muscle is a highly vascularised tissue that contributes approximately 40% of the total body mass. These two factors make it a prime target for secondary cancer metastases. Surprisingly, malignant cancers ...
Isolation of microvesicles and exosomes by microfiltration and estimation of normal reference range in blood plasma.
Current protocols for the isolation of microvesicles (MVs) and exosomes, which in the main focus on differential centrifugation, vary considerably (1). In an attempt to set a new standard, we describe a filtration protocol ...