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Home haemodialysis : trends in technology
(2011-12-01)
Self management and home-based dialysis therapies offer the prospect of improved patient experience and outcomes. To allow more patients to realize these benefits requires changes in technology which focus on maximizing ...
Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses
(2011-06-01)
The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available. Central to cell surface complex formation is binding of lipopolysaccharide ...
Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas
(2011-03-10)
Background: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood, though risk factors include human papillomavirus (HPV). Disruption of HER/PTEN/Akt pathway is present in many cancers; however ...
Women’s spending behaviour is menstrual-cycle sensitive
(2011)
When considering why women are more prone to money pathologies than men the influence of ovarian hormones cannot be ruled out. The phases of the menstrual-cycle are known to have a range of behavioural, psychological and ...