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Human skeletal muscle derived microvesicles induce apoptosis in highly metastatic prostate cancer cells
(2012-09-13)
The human skeletal muscle is a highly vascularised tissue that contributes approximately 40% of the total body mass. These two factors make it a prime target for secondary cancer metastases. Surprisingly, malignant cancers ...
Cancer cell expulsion of anticancer drugs through shedding of microvesicles: association with drug resistance and tumour survival
(2012-09-13)
Microvesicles (MVs) are small (0.1-≤1 µm in diameter) heterogeneous vesicles released from cells constitutively or upon activation, that mediate intercellular communication. Multi-drug resistance (MDR) has been defined as ...