Research publications: Recent submissions
Now showing items 541-560 of 23694
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Differential gene expression in cells with different p53 mutations identifies genome-wide p53 targets and shows distinct modulation of cellular pathways in response to DNA damage
(BioRxiv, 2024-09-06)The fundamental transcription factor p53 regulates cellular processes and integrates signals of cellular stress, triggering a coordinated response to ensure survival of cells restored to healthy function and programmed ... -
Enhancing Local Currency Lending by Multilateral Development Banks: a critical reform agenda
(T20 Brazil, 2024-08-30)This policy brief highlights the crucial role of local currency lending by Multilateral Development Banks (MDBs) in achieving the Sustainable Development Goals (SDGs), particularly in low- and middle-income countries ... -
A Territory-wide Study Investigating the Dose and Efficacy of Different Bacillus Calmette-Guérin Strains in Patients with Intermediate- and High-risk Non–muscle-invasive Bladder Cancer
(2023-10-11)Background Current European Association of Urology (EAU) guidelines support adjuvant intravesical Bacillus Calmette-Guérin (BCG) treatment after Transurethral Resection of Bladder Tumor (TURB) for intermediate- or high-risk ... -
The Relationship Between the Moderate–Heavy Boundary and Critical Speed in Running
(2024-07-24)Purpose: Training characteristics such as duration, frequency, and intensity can be manipulated to optimize endurance performance, with an enduring interest in the role of training-intensity distribution to enhance training ... -
SWOT Analysis and Insights into the Health Research Authority Approval Process for COVID-19 Antimicrobial Stewardship Research in UK Secondary Care: Advocating Think Ethics.
(Research Square Preprints, 2024-01-12)This article examines the Health Research Authority's (HRA) approval process, guided by the 'Think Ethics' principal, for an antimicrobial stewardship (AMS) research project at an English NHS Foundation Trust during the ... -
Urban water infrastructure: A critical review on climate change impacts and adaptation strategies
(2024-11-30)Urban water infrastructure (UWI) plays a critical role in achieving sustainable development goals (SDGs) by providing safe drinking water, sanitation, and wastewater management, and contributing to sustainable cities. ... -
Quality of life, pain and use of analgesic, anxiolytic and antidepressant medication, in people living in care homes
(2024-09-06)BACKGROUND: People living in care homes often have problems with pain, anxiety and depression. Whether being on analgesia, anxiolytics or antidepressants has any bearing on pain severity and quality of life (QoL) in this ... -
Antimicrobial Stewardship Intervention During The COVID-19 Pandemic in the Acute Settings: A Systematic Literature Review
(Research Square Preprints, 2022-08-28)This systematic review investigates Antimicrobial Stewardship (AMS) interventions before (PP) and during the COVID-19 pandemic (DP) in acute care settings. The review synthesises evidence from 16 primary studies published ... -
The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria
(2024-08-16)The impact of cerebral malaria on the transcriptional profiles of cerebral tissues is difficult to study using noninvasive approaches. We isolated plasma extracellular vesicles (EVs) from patients with cerebral malaria and ... -
The future of pensions
(2024-09-13)Labour have promised a review into our pension system and unlock pension capital for “productive” investment. There is no mystery regarding how to make pensions fairer and more stable; what is needed are resources and ... -
Spectroscopic confirmation of two luminous galaxies at a redshift of 14
(2024-09-12)The first observations of the James Webb Space Telescope (JWST) have revolutionized our understanding of the Universe by identifying galaxies at redshift z ≈ 13 (refs. 1–3). In addition, the discovery of many luminous ... -
Intelligent Energy Management across Smart Grids Deploying 6G IoT, AI, and Blockchain in Sustainable Smart Cities
(2024-09-30)In response to the growing need for enhanced energy management in smart grids in sustainable smart cities, this study addresses the critical need for grid stability and efficient integration of renewable energy sources, ... -
The Impact of COVID-19 on Construction Project Performance: A Case Study in Pakistan
(2024-08-16)COVID-19 has had unprecedented effects on construction markets globally due to supply chain disruptions and workforce restrictions, etc. However, construction industries in developing countries are more vulnerable to the ... -
The Global Prevalence of Noise Induced Hearing Impairment Among Industrial Workers : A Systematic Review and Meta-Analysis
(2024-09-09)Noise is one of the harmful health factors in industrial sites. Hearing impairments are one of the most common occupational diseases in a wide range of industries. The aim of this study is to determine the general prevalence ... -
Point-of-care tests of platelet reactivity and clot strength in risk assessment post-PCI: more insight into what really matters
(2024-07-01)This editorial refers to ‘Platelet-fibrin clot strength and platelet reactivity predicting cardiovascular events after percutaneous coronary interventions’, by O. Kwon et al., https://doi.org/10.1093/eurheartj/ehae296.In ... -
P11 Pharmacists’ knowledge, attitudes and perceptions towards antimicrobial stewardship and resistance during the COVID-19 pandemic at secondary care settings in the UK
(2024-08-23)Addressing antimicrobial resistance (AMR) became critical during the COVID-19 pandemic, as inappropriate antibiotic prescribing worsened AMR. The WHO emphasized the need for antimicrobial stewardship (AMS), and the Royal ... -
Patient-Reported Experience Measures to Evaluate and Improve the Quality of Care in Nephrology
(2024-10-03)Patient experience is considered a pillar of high-quality care, integral to patient-centered care, but despite significant policy focus on patient-reported experience measures (PREMs), little is published regarding their ... -
Why premium in freemium: a hedonic shopping motivation model in virtual game retailing
(2024-09-06)Purpose Hedonic shopping is a growing phenomenon designed to enhance gamers’ virtual content shopping experience with increasing economic significance, yet limited attention has been dedicated to this area. Our study ... -
Constraining the Number Density of the Accretion Disk Wind in Hercules X-1 Using its Ionization Response to X-ray Pulsations
(2024-08-22)X-ray binaries are known to launch powerful accretion disk winds that can have a significant impact on the binary systems and their surroundings. To quantify the impact and determine the launching mechanisms of these ...