Research publications: Recent submissions
Now showing items 8141-8160 of 9764
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Analytical quality goals for parathyroid hormone based on biological variation
(2008)Background: Measurement of parathyroid hormone (PTH) is central in the investigation of pathologies of bone and mineral ion metabolism. Knowledge of the biological variation of an analyte forms an essential part of evaluating ... -
“Benign” hypergammaglobulinemic purpura is not benign in pregnancy
(2009)A woman presented at 25 weeks gestation in her first pregnancy with severe preeclampsia and an intrauterine death. It later emerged that she had Waldenstrom’s benign hypergammaglobulinemic purpura. We discuss the implications ... -
Infective spondylodiscitis in patients on high-flux hemodialysis and on-line hemodiafiltration
(2008)Infective spondylodiscitis (ISD) is a rare but potentially devastating condition in hemodialysis (HD) patients. Reports are limited especially in patients receiving high-flux HD and hemodiafiltration (HDF). In a retrospective ... -
Aortoiliac arteriovenous fistula masquerading as deep vein thrombosis
(2008)A male smoker in his 60s with hypertension and hyperlipidaemia presented with progressive swelling of his left leg, abdominal discomfort and oliguria. He was obese and had an extensive left deep vein thrombosis (DVT) ... -
The Pan-Thames EPS study : treatment and outcomes of encapsulating peritoneal sclerosis
(2009)Background: Encapsulating peritoneal sclerosis (EPS) is a disease process that can occur as a complication of peritoneal dialysis (PD). The aim of this study was to make a general assessment of the clinical features, ... -
Molecularly imprinted sol gel for ibuprofen : an analytical study of the factors influencing selectivity
(2009)This paper describes the preparation and testing of a sol gel specific for the non-steroidal anti-inflammatory drug ibuprofen. Ibuprofen was selected as a model compound due to the fact that it contains a number of structural ... -
Revascularization versus medical therapy for renal-artery stenosis
(2009)Atherosclerotic renovascular disease is a common condition with a rate of death of about 16% per year, largely from associated cardiovascular disease.1-3 Stenosis of the renal artery is associated with both hypertension ... -
Low serum osteoprotegerin levels in normoalbuminuric type 1 diabetes mellitus
(2010)The aim of this study is to establish whether abnormal mineral metabolism is present in patients with type 1 DM with normal renal function and in the absence of microalbuminuria. Serum levels of 1,25-dihydroxyvitamin D, ... -
Are low erythropoietin and 1,25-dihydroxyvitamin D levels indicative of tubulo-interstitial dysfunction in diabetes without persistent microalbuminuria?
(2009)Aims: To investigate the relationship between Erythropoietin (EPO) and 1,25-dihydroxyvitamin D levels, and tubular damage in patients with diabetes mellitus (DM) without persistent microalbuminuria. Methods: We measured ... -
UK Renal Registry 11th Annual Report : Chapter 4 ESRD prevalent rates in 2007 in the UK : national and centre-specific analyses
(2009)Introduction: This chapter describes the demographics of UK RRT patients in 2007. Methods: Complete data were electronically collected from 71 UK centres with the remaining 1 centre submitting summary data. A series of ... -
The retained stent : forgotten but not gone
(2010)In 1990, a 23-year-old male patient with cystic fibrosis underwent a successful heart/lung transplantation. His maintenance immunosuppressive regimen included cyclosporine, which led to progressive renal dysfunction secondary ... -
Erythropoietic stress and anemia in diabetes mellitus
(2009)Anemia is one of the world's most common preventable conditions, yet it is often overlooked, especially in people with diabetes mellitus. Diabetes-related chronic hyperglycemia can lead to a hypoxic environment in the renal ... -
Nurturing democracy : the contribution of distributed leadership to a democratic organisational landscape
(2009)This article reviews the comparative merits of distributed leadership and democratic leadership as understandings of, and preferred alternatives to, the leadership of and in organizations. It is particularly concerned that, ... -
Lack of awareness of kidney complications despite familiarity with diabetes : a multi-ethnic qualitative study
(2011)Background: Comparing South Asians with White Europeans and examining the cultural context of any observed differences is a necessary step in achieving culturally competent services and in helping to reduce inequalities ... -
Oxidative stress in early diabetic nephropathy : fuelling the fire
(2011)Diabetic nephropathy is a major microvascular complication of diabetes mellitus and the most common cause of end-stage renal disease worldwide. The treatment costs of diabetes mellitus and its complications represent a ... -
Optimizing home dialysis : role of hemodiafiltration
(2011)Over the last 40 years the technical obstacles which prevented a convective contribution to diffusive dialysis have been overcome. Hemodiafiltration represents a natural evolution of intermittent extracorporeal blood ... -
Do differences in dialysis prescription impact on KDOQI bone mineral targets? The Pan Thames Renal Audit
(2010)Background and Objectives: Patients achieving the Kidney Disease Outcomes Quality Initiative (KDOQI) bone mineral clinical practice guidelines have been reported to have improved survival. Many factors affecting calcium ... -
Still sad after successful renal transplantation : are we failing to recognise depression? An audit of depression screening in renal graft recipients
(2010)Background: Depression is common in chronic physical illness, including renal graft recipients. There is evidence that depression is an independent marker of poorer prognosis in dialysis patients. In the UK, screening is ... -
Dialysis dose in acute kidney injury and chronic dialysis
(2010)The major function of the kidneys is to remove metabolic waste products. Patients with acute kidney injury, especially in the context of multiple-organ failure, are often highly catabolic, and hence have increased production ... -
Late atrial perforation from tunnelled haemodialysis catheter
(2010)Central venous cannulation is a commonly performed procedure in HD patients. One complication associated with such a procedure includes cardiac tamponade, thought to arise from the guidewire, dilator or venous cannula ...