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dc.contributor.authorMcCormick, P A
dc.contributor.authorDick, R
dc.contributor.authorGraffeo, M
dc.contributor.authorWagstaff, D
dc.contributor.authorMadden, A
dc.contributor.authorMcIntyre, N
dc.contributor.authorBurroughs, A K
dc.identifier.citationMcCormick , P A , Dick , R , Graffeo , M , Wagstaff , D , Madden , A , McIntyre , N & Burroughs , A K 1990 , ' The effect of non-protein liquid meals on the hepatic venous pressure gradient in patients with cirrhosis ' , Journal of Hepatology , vol. 11 , no. 2 , pp. 221-5 .
dc.identifier.otherPURE: 309096
dc.identifier.otherPURE UUID: 03f94fad-81ba-4c62-bfb6-5ea5555ce8ee
dc.identifier.otherPubMed: 2254632
dc.identifier.otherScopus: 0025243723
dc.descriptionOriginal article can be found at: Copyright European Association for the Study of the Liver (EASL) [Full text of this article is not available in the UHRA]
dc.description.abstractIt has been suggested that protein feeding increases portal pressure in cirrhotic patients, but that carbohydrate and fat have little effect. We examined the relationship between feeding and portal pressure, using different liquid test meals (250 or 500 ml non-protein, 250 ml protein-containing, 500 ml water), in 29 alcoholic patients with cirrhosis and portal hypertension. The mean hepatic venous pressure gradient (HVPG) increased significantly 30 min after the protein meal (10% increase; p = 0.009) and returned to basal levels at 60 min. The mean HVPG also increased significantly after the non-protein meal: after 500 ml the increase was 23% at 30 min (p = 0.046) and 17% at 60 min (p = 0.12); and after 250 ml it was 15% at 30 min (p = 0.012) and 7% at 60 min (p = 0.05). Ingestion of 500 ml water caused a small, non-significant, increase in mean HVPG. Plasma glucagon levels increased significantly at 30 and 60 min after the protein meal, but did not change significantly after the non-protein meal or water. Both protein-containing and non-protein meals significantly elevate HVPG in alcoholic patients with cirrhosis and portal hypertension.en
dc.relation.ispartofJournal of Hepatology
dc.subjectDietary Proteins
dc.subjectHepatic Veins
dc.subjectHypertension, Portal
dc.subjectLiver Cirrhosis
dc.subjectMiddle Aged
dc.subjectVenous Pressure
dc.titleThe effect of non-protein liquid meals on the hepatic venous pressure gradient in patients with cirrhosisen
dc.contributor.institutionDepartment of Allied Health Professions and Midwifery
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review

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