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dc.contributor.authorBower, P
dc.contributor.authorByford, S
dc.contributor.authorBarber, J
dc.contributor.authorBeecham, J
dc.contributor.authorSimpson, S
dc.contributor.authorFriedli, K
dc.contributor.authorCorney, R
dc.contributor.authorKing, M
dc.contributor.authorHarvey, I
dc.date.accessioned2011-10-18T13:01:08Z
dc.date.available2011-10-18T13:01:08Z
dc.date.issued2003-06-07
dc.identifier.citationBower , P , Byford , S , Barber , J , Beecham , J , Simpson , S , Friedli , K , Corney , R , King , M & Harvey , I 2003 , ' Meta-analysis of data on costs from trials of counselling in primary care: using individual patient data to overcome sample size limitations in economic analyses ' British Medical Journal (Clinical Research ed) , vol. 326 , no. 7401 , pp. 1247-1250 . https://doi.org/10.1136/bmj.326.7401.1247
dc.identifier.issn0959-8138
dc.identifier.otherPURE: 420004
dc.identifier.otherPURE UUID: 396c89a3-3a24-4eb1-a972-90c132f190dc
dc.identifier.otherWOS: 000183480700018
dc.identifier.otherScopus: 0038171298
dc.identifier.urihttp://hdl.handle.net/2299/6705
dc.description.abstractObjective: To assess the feasibility of overcoming sample size limitations in economic analyses of clinical trials through meta-analysis of data on individual patients from multiple trials. Design: Meta-analysis of individual patient data from trials of counselling in primary care compared with usual care by a general practitioner. Setting: Primary care. Patients: People with mental health problems. Main outcome measures: Direct treatment costs, depressive symptoms, and cost effectiveness. Results: Meta-analysis of individual patient data proved feasible. The results showed that the previous analyses of individual trials were underpowered to provide useful conclusions about the cost comparisons. The results are sensitive to assumptions made about the costs of sessions with a counsellor and the management of patients by a general practitioner. Conclusions: Meta-analysis of individual patient data may assist in overcoming sample size limitations in economic analyses. Although feasible, such analysis has shortcomings that may limit the validity of the results. The relative costs and benefits of this method, as opposed to further collection of primary data, are as yet unclear.en
dc.format.extent4
dc.language.isoeng
dc.relation.ispartofBritish Medical Journal (Clinical Research ed)
dc.rights/dk/atira/pure/core/openaccesspermission/open
dc.subjectRANDOMIZED CONTROLLED-TRIAL
dc.subjectNEED
dc.titleMeta-analysis of data on costs from trials of counselling in primary care: using individual patient data to overcome sample size limitations in economic analysesen
dc.contributor.institutionDepartment of Psychology
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
dc.description.versiontypeFinal Published version
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1136/bmj.326.7401.1247
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeopenAccess


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