Show simple item record

dc.contributor.authorWong, W.L.
dc.contributor.authorSonoda, L.I.
dc.contributor.authorGharpurhy, A.
dc.contributor.authorGollub, F.
dc.contributor.authorWellsted, D.
dc.contributor.authorGoodchild, K.
dc.contributor.authorLemon, C.
dc.contributor.authorSaunders, M.
dc.contributor.authorFarrell, R.
dc.identifier.citationWong , W L , Sonoda , L I , Gharpurhy , A , Gollub , F , Wellsted , D , Goodchild , K , Lemon , C , Saunders , M & Farrell , R 2012 , ' 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Assessment of Occult Primary Head and Neck Cancers : An Audit and Review of Published Studies ' , Clinical Oncology , vol. 24 , no. 3 , pp. 190-195 .
dc.identifier.otherORCID: /0000-0002-2895-7838/work/31148138
dc.descriptionCopyright 2011 Elsevier B.V., All rights reserved.
dc.description.abstractAims: To assess the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with squamous cell and undifferentiated cancer neck nodes and no primary site on conventional assessment. Materials and methods: Seventy-eight patients with neck nodal metastases from an unknown primary cancer were studied. PET/CT was carried out in all patients, 1 h after FDG injection. Results: Uptake suspicious of an occult primary cancer was found in 46/78 (59.0%) patients. Subsequent investigations confirmed a primary site in the base of the tongue in 14, pharyngeal palatine tonsil in 14, post cricoid in one, lung in one. PET/CT diagnosed primary cancers in 30/78 patients (38.5%); sensitivity, specificity, positive predictive value, negative predictive value: 30/30 (100.0%), 32/48 (66.7%), 30/46 (65.2%), 32/32 (100.0%), respectively. PET/CT detected additional disease in four patients: contralateral nodal disease in two, mediastinal nodal disease in one and liver metastases in one. Conclusions: FDG PET/CT is of value in the assessment of patients with occult head and neck primary cancers. However, false-positive results remain a limitation of the investigation.en
dc.relation.ispartofClinical Oncology
dc.title18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Assessment of Occult Primary Head and Neck Cancers : An Audit and Review of Published Studiesen
dc.contributor.institutionDepartment of Psychology
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionHealth and Clinical Psychology Research Group
dc.contributor.institutionStatistics and Methodology Research group
dc.contributor.institutionHealth Services Research group
dc.contributor.institutionCentre for Lifespan and Chronic Illness Research
dc.contributor.institutionHealth Services and Medicine
dc.contributor.institutionApplied and Practice-based Research
dc.contributor.institutionBehaviour Change in Health and Business
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record