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dc.contributor.authorFacer, Paul
dc.contributor.authorCasula, Maria A
dc.contributor.authorSmith, Graham D
dc.contributor.authorBenham, Christopher D
dc.contributor.authorChessell, Iain P
dc.contributor.authorBountra, Chas
dc.contributor.authorSinisi, Marco
dc.contributor.authorBirch, Rolfe
dc.contributor.authorAnand, Praveen
dc.date.accessioned2012-05-31T10:03:55Z
dc.date.available2012-05-31T10:03:55Z
dc.date.issued2007
dc.identifier.citationFacer , P , Casula , M A , Smith , G D , Benham , C D , Chessell , I P , Bountra , C , Sinisi , M , Birch , R & Anand , P 2007 , ' Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy ' , BMC Neurology , vol. 7 , pp. 11 . https://doi.org/10.1186/1471-2377-7-11
dc.identifier.otherPURE: 560627
dc.identifier.otherPURE UUID: 4befb068-3c01-4f44-9623-5fbae1dbb4b0
dc.identifier.otherPubMed: 17521436
dc.identifier.otherScopus: 34250857978
dc.identifier.urihttp://hdl.handle.net/2299/8697
dc.description.abstractTransient receptor potential (TRP) receptors expressed by primary sensory neurons mediate thermosensitivity, and may play a role in sensory pathophysiology. We previously reported that human dorsal root ganglion (DRG) sensory neurons co-expressed TRPV1 and TRPV3, and that these were increased in injured human DRG. Related receptors TRPV4, activated by warmth and eicosanoids, and TRPM8, activated by cool and menthol, have been characterised in pre-clinical models. However, the role of TRPs in common clinical sensory neuropathies needs to be established.en
dc.language.isoeng
dc.relation.ispartofBMC Neurology
dc.subjectAxons
dc.subjectCells, Cultured
dc.subjectDiabetic Neuropathies
dc.subjectGene Expression Regulation
dc.subjectHumans
dc.subjectPeripheral Nerve Injuries
dc.subjectPeripheral Nerves
dc.subjectReference Values
dc.subjectTRPM Cation Channels
dc.subjectTRPV Cation Channels
dc.titleDifferential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathyen
dc.contributor.institutionDepartment of Human and Environmental Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1186/1471-2377-7-11
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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