Mathematical modelling of percutaneous absorption
Moss, Gary P.
Wilkinson, Simon C.
This review examines recent progress made in the field of modelling and predicting percutaneous absorption. It describes initial qualitative modelling and how quantitative approaches were pioneered and then developed. particularly in the context of the analysis of specific subsets of data. It then focuses on recent developments, including non-linear modelling and discusses recommendations in model construction, development and validation, suggesting that some models do not fit proposed guidelines