| dc.contributor.author | Gerhard, U. | |
| dc.contributor.author | Searle, M.S. | |
| dc.contributor.author | Williams, D.H. | |
| dc.date.accessioned | 2012-08-23T14:00:45Z | |
| dc.date.available | 2012-08-23T14:00:45Z | |
| dc.date.issued | 1993-01-01 | |
| dc.identifier.citation | Gerhard , U , Searle , M S & Williams , D H 1993 , ' The free energy change of restricting a bond rotation in the binding of peptide analogues to vancomycin group antibiotics ' , Bioorganic and Medicinal Chemistry Letters , vol. 3 , no. 5 , pp. 803-808 . https://doi.org/10.1016/S0960-894X(00)80670-8 | |
| dc.identifier.issn | 0960-894X | |
| dc.identifier.uri | http://hdl.handle.net/2299/8941 | |
| dc.description | Copyright 2004 Elsevier B.V., All rights reserved. | |
| dc.description.abstract | The adverse cost in free energy of restricting an internal bond rotation in the binding of the peptide ligands N-succinyl-D-alanine and N-fumaryl-D-alanine to the antibiotic Ristocetin A, has been estimated to be 3.7 ± 0.9 kJ mol per rotor by comparison of the difference in free energies of binding measured by UV spectrometry. | en |
| dc.format.extent | 6 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Bioorganic and Medicinal Chemistry Letters | |
| dc.title | The free energy change of restricting a bond rotation in the binding of peptide analogues to vancomycin group antibiotics | en |
| dc.contributor.institution | School of Life and Medical Sciences | |
| dc.description.status | Peer reviewed | |
| dc.identifier.url | http://www.scopus.com/inward/record.url?scp=0027241298&partnerID=8YFLogxK | |
| rioxxterms.versionofrecord | 10.1016/S0960-894X(00)80670-8 | |
| rioxxterms.type | Journal Article/Review | |
| herts.preservation.rarelyaccessed | true | |
