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dc.contributor.authorAhmad, Z.
dc.contributor.authorVargas-Reus, M.A.
dc.contributor.authorBakhshi, R.
dc.contributor.authorRyan, F.
dc.contributor.authorRen, Guogang
dc.contributor.authorOktar, F.
dc.contributor.authorAllaker, R.
dc.date.accessioned2013-02-11T11:29:59Z
dc.date.available2013-02-11T11:29:59Z
dc.date.issued2012-04-16
dc.identifier.citationAhmad , Z , Vargas-Reus , M A , Bakhshi , R , Ryan , F , Ren , G , Oktar , F & Allaker , R 2012 , ' Antimicrobial properties of electrically formed elastomeric polyurethane–copper oxide nanocomposites for medical and dental applications ' , Methods in Enzymology , vol. 509 , pp. 87-99 . https://doi.org/10.1016/B978-0-12-391858-1.00005-8
dc.identifier.issn1557-7988
dc.identifier.otherPURE: 859085
dc.identifier.otherPURE UUID: 958b55d9-a166-4863-b183-7e0acde392d9
dc.identifier.otherScopus: 84860742300
dc.identifier.otherORCID: /0000-0001-8865-1526/work/32373265
dc.identifier.urihttp://hdl.handle.net/2299/9937
dc.description.abstractWith the rapidly advancing field of nanotechnology having an impact in several areas interfacing life and physical sciences, the potential applications of nano-particles as antimicrobial agents have been realized and offer great opportunities in addressing several viral and bacterial outbreak issues. Polyurethanes (PUs) are a diverse class of polymeric materials which also have applications in several areas of biomedical science ranging from blood contact devices to implantable dental technologies. In this report, copper oxide (CuO) nanoparticles (mean size $50 nm) are embedded into a PU matrix via two electrical fabrication processes. To elucidate the antimicrobial activity, a range of different loading compositions of CuO within the PU matrix (0%, 1%, 5%, and 10% w/w) are electrospun to form thin porous films (thickness<10mm). After washing, the films are tested for their antimicrobial properties against methicillin-resistant Staphylococcus aureus (MRSA). Significant reduction of populations was demonstrated with 10% w/w CuO over a 4-h period. This approach demonstrates the potential of generating tailored antimicrobial structures for a host of applications, such as designer filters, patterned coatings, breathable fabrics, adhesive films (as opposed to sutures), and mechanically supporting structures.en
dc.format.extent11
dc.language.isoeng
dc.relation.ispartofMethods in Enzymology
dc.titleAntimicrobial properties of electrically formed elastomeric polyurethane–copper oxide nanocomposites for medical and dental applicationsen
dc.contributor.institutionSchool of Engineering and Technology
dc.contributor.institutionScience & Technology Research Institute
dc.contributor.institutionCentre for Engineering Research
dc.contributor.institutionMaterials and Structures
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Engineering and Technology
dcterms.dateAccepted2012-04-16
rioxxterms.versionofrecordhttps://doi.org/10.1016/B978-0-12-391858-1.00005-8
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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