Analysis in Comparative Study on Antimicrobial Stewardship and Antibiotic Prescribing: 2019 vs. 2020 COVID-19 Era.

This research examines antimicrobial stewardship (AMS) and antibiotic prescribing in a UK NHS Foundation Trust before and during the COVID-19 pandemic. It explores the impact of the pandemic on AMR and AMS practices using a systematic literature review, retrospective medical records analysis, and a prospective survey. Key findings include shifts in antimicrobial use, prescribing patterns, and healthcare professionals' attitudes towards AMS. This study highlights the challenges and adaptations in AMS during a global health crisis, offering valuable insights for healthcare systems worldwide. It highlights the need for continued vigilance and innovation in AMS to combat AMR effectively, particularly during pandemics.