Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis

Mader, K. T.; Tetteh, J.; McAuley, W. J.; Lane, M. E.; Hadgraft, J.; Andanson, J. M.; Kazarian, S. G.

Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis

Mader, K. T., Tetteh, J., McAuley, W. J., Lane, M. E., Hadgraft, J., Andanson, J. M. and Kazarian, S. G. (2010) Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis. Journal of Pharmacy and Pharmacology (10). pp. 1279-1280. ISSN 0022-3573

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ATR-FTIR spectroscopic imaging permeation experiments of a model formulation across stratum corneum (SC) were conducted to acquire further understanding of the mechanism of drug permeation. Quantitative iterative target transformation factor analysis (QITTFA) was used for the analysis of the complex and highly overlapping spectroscopic data generated.

Item Type	Article
Date Deposited	29 May 2025 09:10
Last Modified	29 May 2025 09:10

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McAuley, W. J.

Journal of Pharmacy and Pharmacology

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