Aryl sulfones : A new class of γ-secretase inhibitors

Teall, M., Oakley, P., Harrison, T., Shaw, D., Kay, E., Elliott, J., Gerhard, U., Castro, J.L., Shearman, M., Ball, R.G. and Tsou, N.N. (2005) Aryl sulfones : A new class of γ-secretase inhibitors. Bioorganic and Medicinal Chemistry Letters (10). pp. 2685-2688. ISSN 0960-894X
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The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors for the potential treatment of Alzheimer's disease is described

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