Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide
Reimann, M., Vafeiadou, K., Hall, W. L., Dierkes, J., Nilsson, M., Dahlman-Wright, K., Ferrari, M., Huebner, U., Hallund, J., Bugel, S., Branca, F., Williams, C. M. and Koebnick, C.
(2006)
Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide.
Climacteric : the Journal of the International Menopause Society (3).
pp. 215-23.
ISSN 1369-7137
Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease (CVD). Both amino acids can be reduced in vivo by estrogen. Variation in the estrogen receptor (ER) may influence homocysteine and ADMA, yet no information is available on associations with single nucleotide polymorphisms in the estrogen receptor genes ERalpha (PvuII and XbaI) and ERbeta (1730G-->A and cx + 56 G-->A).
| Item Type | Article |
|---|---|
| Keywords | Aged; Arginine; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Single Nucleotide; Postmenopause; Risk Factors; Vitamin B 12 |
| Date Deposited | 29 May 2025 09:11 |
| Last Modified | 29 May 2025 09:11 |