The synthesis and optical properties of Cu–In–S/ZnS nanocrystals in buffer solution for near-infrared fluorescence imaging

Mann, Patrick, Bourke, Struan, Urbano, Laura, Morgan, David J., Dailey, Lea Ann, Centelles, Miguel, Thanou, Maya, Long, Nicholas J. and Green, Mark A. (2025) The synthesis and optical properties of Cu–In–S/ZnS nanocrystals in buffer solution for near-infrared fluorescence imaging. Journal of Materials Chemistry B, 13 (20). pp. 5871-5879. ISSN 2050-7518
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In this report, we present a novel one-pot synthesis of Cu–In–S/ZnS quantum dots (QDs) in buffer solution as a facile route to biocompatible nanoscale imaging probes, with emission wavelengths as far as 675 nm in the biologically important near-infrared spectral region and quantum yields of up to 16%. Whilst a simple route, our method produced particles that displayed exceptionally high cell viability with facile applications in in vivo imaging, highlighting the potential of these QDs as advanced imaging probes.


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