Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis : experience in the ERAN inception cohort

McWilliams, Daniel F., Kiely, Patrick D. W., Young, Adam and Walsh, David A. (2013) Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis : experience in the ERAN inception cohort. BMC Musculoskeletal Disorders, 14: 153. ISSN 1471-2474

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Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.

Item Type	Article
Identification Number	10.1186/1471-2474-14-153
Additional information	© 2013 McWilliams et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Keywords	adult, aged, antirheumatic agents, arthritis, rheumatoid, cohort studies, disability evaluation, drug substitution, drug therapy, combination, drug-related side effects and adverse reactions, female, health status, humans, hydroxychloroquine, logistic models, male, methotrexate, middle aged, sulfasalazine, treatment failure, treatment outcome
Date Deposited	15 May 2025 12:45
Last Modified	25 Feb 2026 00:32