Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

Cook, Michael T., Smith, Sarah L. and Khutoryanskiy, Vitaliy V. (2015) Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing. Chemical Communications, 51. pp. 14447-14450. ISSN 1359-7345
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Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion


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