Bacterial endotoxin rapidly stimulates prolonged endothelium-dependent vasodilatation in the isolated perfused rat heart

Baydoun, A. R., Foale, R. D. and Mann, G.E. (1993) Bacterial endotoxin rapidly stimulates prolonged endothelium-dependent vasodilatation in the isolated perfused rat heart. British Journal of Pharmacology, 109. pp. 987-991. ISSN 0007-1188
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The effects of bacterial lipopolysaccharide (Escherichia coli 0111-B4; LPS) on coronary vascular tone were examined in the isolated perfused rat heart. The role of nitric oxide and/or prostaglandin products of the cyclooxygenase pathway in mediating the actions of LPS were also investigated.


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