UH Research Archive: Recent submissions
Now showing items 9361-9380 of 11145
-
All patients receiving renal replacement therapy in the United Kingdom in 2005 (chapter 4)
(2007)Summary data are provided for the whole United Kingdom. There were 41 776 adult patients alive on renal replacement therapy (RRT) in the UK at the end of 2005, a prevalence for adults of 694 pmp. Addition of 748 children ... -
Mechanisms of disease : the hypoxic tubular hypothesis of diabetic nephropathy
(2008)Diabetic nephropathy is traditionally considered to be a primarily glomerular disease, although this contention has recently been challenged. Early tubular injury has been reported in patients with diabetes mellitus whose ... -
Depression on dialysis
(2008)Depression is the most common psychopathological condition among patients with end-stage renal disease (ESRD), yet it is still under-recognized and misdiagnosed. Depression reduces quality of life and has a negative clinical ... -
Screening for depression while patients dialyse : an evaluation
(2008)Background: The lack of routine depression screening among the haemodialysis (HD) population may contribute to depression being under-recognised. While screening patients could be beneficial, the optimum screening procedure ... -
Factors affecting long-term survival of tunnelled haemodialysis catheters—a prospective audit of 812 tunnelled catheters
(2008)Background: In 2001, in the US, 23% of haemodialysis patients were dialysing through tunnelled venous catheters (TVCs), and in the UK (2006) there were 28% of prevalent patients using catheters. It is unlikely that numbers ... -
Synthesis of bioinorganic antimicrobial peptide nanoparticles with potential therapeutic properties
(2008)Amphiphilicity and cationicity are properties shared between antimicrobial peptides and proteins that catalyze biomineralization reactions. Merging these two functionalities, we demonstrate a reaction where a cationic ... -
Effect of high haematocrit on the efficiency of high-flux dialysis therapies
(2008)Background/Aims: Left ventricular (LV) hypertrophy is a powerful predictor of mortality in dialysis patients. Serial measurements of LV mass provide prognostic information. We evaluated the association between changes in ... -
Analytical quality goals for parathyroid hormone based on biological variation
(2008)Background: Measurement of parathyroid hormone (PTH) is central in the investigation of pathologies of bone and mineral ion metabolism. Knowledge of the biological variation of an analyte forms an essential part of evaluating ... -
“Benign” hypergammaglobulinemic purpura is not benign in pregnancy
(2009)A woman presented at 25 weeks gestation in her first pregnancy with severe preeclampsia and an intrauterine death. It later emerged that she had Waldenstrom’s benign hypergammaglobulinemic purpura. We discuss the implications ... -
Infective spondylodiscitis in patients on high-flux hemodialysis and on-line hemodiafiltration
(2008)Infective spondylodiscitis (ISD) is a rare but potentially devastating condition in hemodialysis (HD) patients. Reports are limited especially in patients receiving high-flux HD and hemodiafiltration (HDF). In a retrospective ... -
Aortoiliac arteriovenous fistula masquerading as deep vein thrombosis
(2008)A male smoker in his 60s with hypertension and hyperlipidaemia presented with progressive swelling of his left leg, abdominal discomfort and oliguria. He was obese and had an extensive left deep vein thrombosis (DVT) ... -
The Pan-Thames EPS study : treatment and outcomes of encapsulating peritoneal sclerosis
(2009)Background: Encapsulating peritoneal sclerosis (EPS) is a disease process that can occur as a complication of peritoneal dialysis (PD). The aim of this study was to make a general assessment of the clinical features, ... -
Molecularly imprinted sol gel for ibuprofen : an analytical study of the factors influencing selectivity
(2009)This paper describes the preparation and testing of a sol gel specific for the non-steroidal anti-inflammatory drug ibuprofen. Ibuprofen was selected as a model compound due to the fact that it contains a number of structural ... -
Revascularization versus medical therapy for renal-artery stenosis
(2009)Atherosclerotic renovascular disease is a common condition with a rate of death of about 16% per year, largely from associated cardiovascular disease.1-3 Stenosis of the renal artery is associated with both hypertension ... -
Low serum osteoprotegerin levels in normoalbuminuric type 1 diabetes mellitus
(2010)The aim of this study is to establish whether abnormal mineral metabolism is present in patients with type 1 DM with normal renal function and in the absence of microalbuminuria. Serum levels of 1,25-dihydroxyvitamin D, ... -
Are low erythropoietin and 1,25-dihydroxyvitamin D levels indicative of tubulo-interstitial dysfunction in diabetes without persistent microalbuminuria?
(2009)Aims: To investigate the relationship between Erythropoietin (EPO) and 1,25-dihydroxyvitamin D levels, and tubular damage in patients with diabetes mellitus (DM) without persistent microalbuminuria. Methods: We measured ... -
UK Renal Registry 11th Annual Report : Chapter 4 ESRD prevalent rates in 2007 in the UK : national and centre-specific analyses
(2009)Introduction: This chapter describes the demographics of UK RRT patients in 2007. Methods: Complete data were electronically collected from 71 UK centres with the remaining 1 centre submitting summary data. A series of ... -
The retained stent : forgotten but not gone
(2010)In 1990, a 23-year-old male patient with cystic fibrosis underwent a successful heart/lung transplantation. His maintenance immunosuppressive regimen included cyclosporine, which led to progressive renal dysfunction secondary ... -
Erythropoietic stress and anemia in diabetes mellitus
(2009)Anemia is one of the world's most common preventable conditions, yet it is often overlooked, especially in people with diabetes mellitus. Diabetes-related chronic hyperglycemia can lead to a hypoxic environment in the renal ... -
Nurturing democracy : the contribution of distributed leadership to a democratic organisational landscape
(2009)This article reviews the comparative merits of distributed leadership and democratic leadership as understandings of, and preferred alternatives to, the leadership of and in organizations. It is particularly concerned that, ...